Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID74034	Mitoxantrone	GSE92742	PHH	Human	6h	2.5uM	EID0413

Response Information :

Types	Number	Response transcription factors
Up-regulation	48	FOS; BIRC2; CTNNB1; NFKBIB; PFDN5; CTBP2; MYCN; TBX1; HMGB2; CNBP; CITED2; CARHSP1; KLF11; ZNF177; PEG3; ARID5B; HMGB3; LYL1; TOX; RNF138; TULP3; SHOX2; BACH2; HDAC9; MBD2; SOX17; TCERG1; ZNF354A; MYBL2; MYCL; HOXC6; HHEX; FOXL2; ZBTB18; ISL1; ERBB4; BCL11A; AEBP1; MYBL1; ASCL1; INSM1; ZNF83; KLF6; MNDA; TCF21; PBX3; IFI16; WT1
Down-regulation	93	MYC; NFKBIA; GABPB1; KAT7; IKBKAP; CEBPA; SKI; ZNF629; PLAGL2; NUP62; GTF2IRD1; TSC22D1; ZNF574; NFE2L1; MLXIPL; CAPN15; ZNF652; CITED1; FOXK2; CHD9; SIX1; SERTAD2; LITAF; PMF1; ZNF12; SOX10; POLR2A; ZNF430; CCDC59; MED24; ZNF14; NFIL3; MED1; GATAD2A; HDAC6; ERF; MED6; NCOA3; RLF; SOX9; ZNF274; BCL3; SNAI2; NRIP1; SMAD3; PITX1; PDLIM1; CCNH; ELF1; PBX2; SMARCD2; XBP1; SIX2; CDC5L; NCOR2; MED13; SOX4; RELB; TFAM; CREB3L2; SMAD7; PCGF2; SLC2A4RG; HEY1; BTG1; JARID2; TP53; CD3D; CALR; POU2AF1; ELF5; NR1H3; RBL2; EGR3; PPARD; MYCBP; RFX5; BRD2; KLF5; STAT6; CRK; FOXC1; PURA; ZNF587; IRF4; TRIM29; TXNIP; ERBB2; TSC22D3; LEF1; TFAP2A; ABL1; ZNF586