Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID74018	Cucurbitacin-i	GSE92742	PHH	Human	6h	2.5uM	EID0413

Response Information :

Types	Number	Response transcription factors
Up-regulation	89	EGR1; XBP1; MMS19; EGR2; AFF1; GABPB1; SERTAD2; PCGF2; AATF; FOXO1; EGR3; PAX8; RNF10; BRD3; REPIN1; ZBTB16; CUX1; SMARCE1; TAF1D; NRBF2; FHL2; NFE2L1; PHF20; NCOA6; MXD1; LMCD1; SOX10; ATF3; KLF4; PTRF; MLX; MED1; SP140; RXRA; NCOR2; EDF1; PURA; ELF1; MSX1; ZMYND8; NCOA4; ENO1; SALL1; BTAF1; PPARGC1A; PPARG; BRD8; ZMIZ2; RERE; BHLHE40; KLF1; HOXB7; CREB5; NFIL3; SMARCA2; MAFG; ELF5; RBPMS; RREB1; MAFF; SPEN; PPARD; STAT5A; WWC1; TFDP1; RFX5; ZBTB18; PRRX1; FOSB; KLF6; MTA1; CREB3L2; YWHAB; ZIC1; TSC22D3; NR2F2; BIRC2; BAZ1A; ERBB2; KLF9; HES1; TRIP6; ZNF652; EYA2; ARID5B; PDLIM1; HOXC6; ABL1; KDM5D
Down-regulation	76	POU4F2; HMG20B; ZFP30; CDK2; FOXO4; NHLH1; YEATS4; SUMO1; ZNF195; DNMT1; ZNF43; CBX4; PBX2; INSM1; STAT4; HIC2; JUP; ISL1; ZNF124; E2F2; ZNF529; ZNF415; MYT1L; MEIS2; PFDN5; USP16; ZNF14; ILF2; ZNF606; ZNF117; FOXA1; RSF1; SIX3; JUND; VPS72; MAZ; SOX11; MYCL; SHOX2; BCL11B; RBFOX2; TFAP2A; ZFPM2; SMAD7; FOXF2; TDP2; NEUROD1; ZNF551; MYBL1; SMAD6; ZNF329; FOXF1; PEG3; PBXIP1; IRF9; HMGB3; ZNF544; HMGA1; DACH1; ZBED2; WT1; STAT1; DLX2; TBX3; TCF21; PBX1; ATF1; ERBB4; IRF8; ZNF331; HOXB2; TCF4; ZNF83; NR2F1; MEIS1; ZNF586