Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID74017	Cucurbitacin-i	GSE92742	PHH	Human	6h	10uM	EID0413

Response Information :

Types	Number	Response transcription factors
Up-regulation	88	EGR1; FOSL1; EGR2; DDIT3; EGR3; XBP1; NRBF2; ZNF614; SKIL; AFF4; TRIM25; PTRF; BLZF1; MAFF; ZBTB11; KLF3; ZNF217; IKZF5; SERTAD2; FOXO1; TRIP4; DLX5; RBM39; ATF3; CUX2; BACH1; ZNF430; PAX8; SMAD3; NFIL3; SOX10; GABPB1; WWP1; RNF10; EGR4; ATF4; PRPF6; TCF7L2; CNBP; SP140; KLF6; LYL1; HOXB6; MXI1; NCOA2; ELF5; FOXC1; TRPS1; TP63; ANKRD1; ZNF91; FOXN3; FOXE1; COPS5; PIR; ARNTL; ZSCAN31; CSDE1; ZNF304; ZNF586; ZNF329; NKX3-1; LITAF; WWC1; FOSL2; BCL6; ETS1; TFAP2A; TGFB1; ARID5B; IRF4; ENO1; CITED2; KDM5D; PAWR; TRIM29; NRIP1; TFAP2C; MNDA; ST18; FOSB; SNAI2; KLF5; PPARD; PDLIM1; TRIM22; SOX9; BHLHE41
Down-regulation	79	HOXA5; FOXO4; TCF4; TAF5L; CDX2; CBX5; TCF15; FOXJ1; CDX1; CNOT2; KDM2A; NR1I2; MXD4; IRF2; PA2G4; NR3C2; NFKBIA; MAX; HDAC7; NELFB; HOXC4; ID3; ING2; PBX2; SMAD7; TLE2; ZNF768; CDK8; ZNF3; SFPQ; CREBZF; NR2F1; TSC22D4; HDAC4; TCF3; SIAH2; HMGB1; HOXA7; YBX2; SMARCD3; POU2AF1; SATB2; HIC2; CHD4; HMGB3; PBX1; ABL1; MEIS1; MTF2; DACH1; SUV39H1; HDAC1; ZNF423; HOXD11; HMG20B; MAZ; SOX11; ID1; PBXIP1; HIRA; KLF13; SMAD1; PAX6; WT1; HOXA10; PLAGL1; NR4A2; SPEN; MAGED1; FOXG1; BCL3; STAT1; HMGB2; ZBTB20; BASP1; INSM1; LEF1; FOXF1; IKZF1