Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID74016	Vorinostat	GSE92742	PHH	Human	6h	10uM	EID0412

Response Information :

Types	Number	Response transcription factors
Up-regulation	152	KAT6A; HLX; RUVBL1; LOXL2; SUMO1; TFAP2A; BACH2; DNMT1; DLX2; ZNF268; ID3; NEUROD1; NR4A2; CDK2; ZSCAN9; NR2E1; ARNT2; NOC2L; IKZF1; ZNF711; ZNF180; PIAS4; RAD21; ZNF93; SOX18; SOX2; HMGXB4; SOX13; FOXF2; VPS72; VDR; INSR; PBXIP1; SOX11; ING4; MYBL1; NR4A1; TRIM24; SSBP2; CDIP1; ZFP30; BRIP1; POLR3C; IRF6; ZNF423; HHEX; ZNF43; MYBL2; PRDM2; ZNF112; IFI16; MEIS2; ZFPM2; ESRRG; ILF2; ZNF573; NHLH2; ZNF768; INSM1; CERS6; SHOX2; HIPK1; MED14; ARID4B; TCEA2; ZNF354A; ZNF623; BCL10; SALL2; ATF3; GATA6; JUN; CBFA2T2; SP2; FOXM1; HBP1; CNBP; PTTG1; ST18; ZNF107; MED17; FOXG1; ATN1; MYT1L; SNAI2; CUX2; PBX3; TRPS1; LEF1; SMAD1; PRKDC; NR5A2; HOXD1; MYCL; EP300; TULP3; ZNF281; HEY1; CNOT2; TOX; PAX6; ZNF426; SPDEF; SOHLH2; PLAG1; SALL1; SOX17; ZNF415; E2F5; HOXD3; HIRA; CBFA2T3; KLF10; RUNX1; ACTL6A; HIC2; TCF7L1; TGFB1I1; ZEB1; PPARD; FOSB; ERBB4; ID1; CTBP1; HMGA1; NKX2-1; PHIP; SOX9; MECOM; PSMC3; TCF21; ZNF83; GTF2A2; EN1; ELF3; FOXF1; ZNF304; FOXD1; ARID5B; GLI2; WT1; HES1; NR2F1; MEIS1; ZIC1; FOS; PBX1; JUP; ZNF331; CITED2; ZBTB18; ESR1
Down-regulation	158	MYC; APEX1; IKBKAP; NCOA4; CCNA2; RHOA; PAX8; ATF5; NUP62; PPARG; CASZ1; RARB; ELF1; CXXC1; ARNTL; RBM14; RELA; BCLAF1; TP53; STAT2; SOX4; SMAD2; AFF1; NPM1; HIPK3; ATF1; RNF14; NFE2L1; NFKB1; MBD1; PSPC1; MYNN; SIX3; USP22; GABPB1; CNOT1; ZBTB1; ZMIZ2; CREB3L2; POLR2A; HLF; NR0B1; MED1; STAT5B; BRD2; REPIN1; LIMD1; TRIM16; STAT5A; CBFB; SREBF1; BRD8; ZBTB38; SNW1; KLF5; ZBTB11; ZMYM2; UIMC1; ASH2L; BAZ1A; TFCP2L1; CEBPA; FOXO3; AIP; ARNTL2; ZNF692; NFYA; MSC; XBP1; STAT6; PURA; IRF7; TBL1XR1; NRBF2; RNF141; KLF3; HLTF; LPIN2; MAF; TRIM22; PRPF6; ZFP64; KAT2A; ZHX2; RREB1; RXRA; BRD3; MEOX1; SPEN; SUV39H1; UBE2L3; DPF2; KAT8; TRIP6; BHLHE40; RBBP4; PPARGC1A; SMARCE1; KDM2A; CREB5; DDX5; BTG1; RYBP; CTR9; RBPJ; HOXA7; SAP18; TGIF1; PIR; REST; NKX3-1; TCF12; FOSL1; CRYM; KDM5D; ZNF148; VEZF1; CHD9; RFX5; MAGED1; TCERG1; EDF1; HDAC6; FOXA2; BIRC2; SMAD7; SMARCA1; CREM; ZNF512B; CDYL; STAT3; PITX1; IRF4; TLE2; HTATIP2; TAF4; TRIM29; ABL1; ZNF131; MYRF; BCL11B; SMAD3; BMI1; TRIM28; HOXC6; BBX; FOXO1; ENO1; TLE1; PLAGL1; NR1D2; KLF4; HMGN3; NFIB; FLNA; NR1H2; TBL1X; CRK