Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID73956	Mitoxantrone	GSE92742	PHH	Human	6h	2.5uM	EID0412

Response Information :

Types	Number	Response transcription factors
Up-regulation	54	CNBP; INSM1; TBX1; NR0B2; GLI2; SOX18; HDAC1; ZNF423; GFI1B; POU2AF1; MDM2; MYT1; TFAP2A; TAF10; TCF21; ERG; AEBP1; POU4F1; GTF2I; BNC2; NFE2L3; TWIST1; HMGA1; TGFB1I1; ARNT2; MYBL1; COPS5; ASCL1; NKX2-1; TCF4; COPS2; HIRA; RUNX3; DLX2; FOXD1; PPARD; KAT6B; CBFA2T3; MEOX2; MYCBP; SOX11; NEUROD1; ZFP36L2; CUX2; ZFPM2; TRIM22; NKX2-2; WWTR1; PSIP1; HHEX; FOSB; ARID5B; PBX3; HOXA5
Down-regulation	154	APEX1; MYC; CEBPB; NFIL3; CEBPA; FOSL2; E2F6; BCL6; ZNF189; ZNF473; ECD; SMAD1; ADNP; SAFB2; PLAGL2; ZNF45; NCOA6; ZNF140; TAF1D; ZXDC; SMARCD1; ELK4; HIVEP1; MAML1; RCOR3; HDAC4; ZNF672; RCOR1; SAP30; TBL1X; REST; ZNF629; TRIM27; TRRAP; NR3C1; ING2; ETS2; VEZF1; SP3; POLR3C; CREB3L2; TRIM32; TOB1; LPIN2; NFYA; MED7; XBP1; BHLHE40; ZNF266; RNF14; ATF1; ZNF14; GTF2IRD1; ZBTB18; SMAD3; HMGXB4; PCGF3; FOXK2; BLM; SUV39H1; SREBF1; AR; BACH1; PPARGC1A; AFF1; ZNF443; RNF6; ZMYND11; SUZ12; DEAF1; ZNF432; YAP1; SUPT3H; NCOA1; SETD2; CHD8; MAX; MXD4; THAP1; PMS1; TGIF1; MKL2; NAB1; ZNF7; BRD3; CDC5L; ZNF131; NKX3-1; ZNF146; PITX1; TSC22D1; DPF2; RYBP; ZNF148; EGR3; TRIM16; CENPF; ZNF430; PSPC1; FOSL1; BCL3; FOXJ3; AHR; RBBP8; HLF; NR4A1; ZNF12; ELF3; ATF3; ZBED1; ZNF512B; KLF10; KLF5; PAX8; MAF; TRIM29; BIRC2; CEBPG; SIAH2; HOXB2; TCERG1; ZNF264; ZNF468; WWC1; ZBED2; PURA; MEIS1; VGLL4; CHD7; BTG1; ZNF134; NR1H2; EED; MITF; FOXO1; CREB1; NRIP1; ZBTB20; TP63; HMGN3; ZBTB16; HES1; ZNF544; RFX5; ZNF211; CD3D; TCF7L2; EYA2; WT1; BHLHE41; MTA1; MAFB; ID1; ZNF586