Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID73878	Mitoxantrone	GSE92742	PHH	Human	6h	2.5uM	EID0411

Response Information :

Types	Number	Response transcription factors
Up-regulation	113	EPAS1; KAT8; MAK; MYT1; BACH2; ZNF688; PRDM2; RFX2; ZNF197; ZBTB18; ZNF667; CBX4; HIVEP2; ZNF506; ZNF232; ID3; GTF3A; ZNF107; ZHX2; CNBP; NHLH2; CDK8; ENY2; PTRF; HAND1; NEUROD1; SOX17; ING4; ZNF589; FHL5; ZNF354A; ZBTB16; ZNF430; YEATS4; FUBP1; ZFPM2; BAZ2A; ZKSCAN1; MYBL1; ZBED2; SRCAP; POU5F1B; ZNF93; CALCOCO1; CBFA2T3; GRHL2; MKL2; ZNF91; PAX5; HIPK1; FLI1; ELF5; ZNF652; ZNF423; TCF21; AEBP1; DEK; PFDN5; PEG3; NR4A1; BBX; PEX2; SSBP2; SNAI2; ATN1; NKX2-1; LEF1; ZNF224; RYBP; RB1; ZSCAN18; ACTL6A; PITX2; SOX11; INSM1; KAT2B; MLXIP; ZNF665; ZEB1; SMARCD3; MTA1; EHF; UBP1; TCF7L1; ZNF83; TGFB1I1; PBX1; TULP3; ZBTB38; CREBL2; DRAP1; ZNF117; ZNF264; AHR; CREB1; ZNF12; WWTR1; ST18; ZNF266; ERBB4; ETS1; MTF2; BASP1; TFAP2C; TXNIP; MEIS2; HOXA5; VPS72; IRF6; PBX3; SPEN; ARNT2; ID1
Down-regulation	166	APEX1; XBP1; MAFG; IKBKAP; CDK7; ERCC3; CREB3L1; CCNA2; ZBED1; JUND; KAT5; NRBF2; SAP30; SNIP1; TRIP4; PPARD; ZNF432; PA2G4; ECD; MYCBP; MXD1; GATAD2A; FHL2; SAP130; SP3; HDAC4; ADNP2; SFPQ; ZNF212; SIX1; MAF; PITX1; URI1; DPF2; AFF1; SAFB; EWSR1; SMAD1; CIZ1; NCOA4; HEY1; SP2; TGFB1; NFIL3; TCERG1; NFX1; IRF2; ZMYND11; RBBP7; SOX9; GABPA; SND1; SATB2; CEBPA; BACH1; NFE2L2; KLF6; ZSCAN31; ZNF189; CENPF; NCOR2; NR1I2; DR1; SAFB2; MYC; SMARCA2; E2F6; NAB1; SMAD2; TFCP2; FOXD1; PIR; NCOA6; ZBTB43; MGA; ZNF45; EYA2; KLF11; RBBP4; NPAS2; SMAD3; HMGB2; SUB1; FOXM1; CNOT1; NFYC; HNRNPD; ARID3A; REST; FLNA; TGIF1; PBXIP1; TCF25; TSC22D4; UBE2I; FOXO3; ZBTB1; SALL1; ORC2; ZNF512B; KLF2; ZFP36L2; MEOX2; TCF3; ETV1; TFDP1; HOXD1; RBM14; YAP1; KAT6B; RNF138; ETV4; TBL1X; ID2; ZNF473; HMGB3; PLAGL1; POLR2A; POU4F1; HDAC6; IRF9; TRIP6; CBFB; CCNE1; BHLHE40; RREB1; MED1; KDM5D; BRD4; SIX2; FOSL2; RNF4; SHOX2; ZIC1; TLE1; HOXC10; HLTF; RUNX3; HES1; HIRA; GATA6; SOX4; PPARG; HMGA2; SMARCC1; CITED2; KLF5; DNMT3B; NR1H2; TAF1D; NUP62; ZNF217; MECOM; STAT1; PRKDC; SATB1; PLAGL2; BIRC2; BRD2; NKX3-1; MNDA; OSR2; RFX5; IFI16; ELF3; WT1