Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID73877	Mitoxantrone	GSE92742	PHH	Human	6h	10uM	EID0411

Response Information :

Types	Number	Response transcription factors
Up-regulation	128	MEF2C; IKZF1; GATA1; CIC; NFATC4; HOXA3; KLF15; CRTC1; RORC; RAX; ESRRG; GBX1; ZNF711; MLXIPL; HSF4; NHLH1; SSBP3; EVX1; RARG; ZNF671; TFAP4; GTF2IRD1; TWIST1; DACH1; ZNF528; HDAC7; ZNF35; GATA6; ZNF816; OVOL2; MNAT1; SMARCD3; MYB; MDM2; ZNF76; HOXB1; FOXI1; CBX4; ZNF93; TSHZ2; ZNF215; SPI1; NHLH2; HAND1; ZNF532; KLF7; SOX11; HOXA4; ZNF91; ZNF224; TADA3; SRCAP; PCGF3; KLF1; ZNF253; CIITA; HSF1; PPP1R13L; KLF11; GTF2I; CSDC2; ZSCAN9; ING4; RUNX1; CDX1; JUP; ZNF160; NR4A2; PBX2; LYL1; PRRX1; CNOT2; NR4A1; AES; TBPL1; ZNF665; NR1H4; NEUROD1; ETS2; HOXA5; EYA1; ELK3; CREG1; HSBP1; ZNF611; ZIC3; PAWR; CBX3; TGFB1; ZNF136; CTBP2; BCL11B; GTF3A; MTA1; ZNF117; DAXX; ZNF264; TGFB1I1; MTF2; CITED2; KDM5D; TCF21; WT1; ZBTB20; TCF4; DRAP1; CREB1; PFDN5; NR1H2; ZNF544; TRIM16; ZFPM2; CREBL2; INSM1; ARID5B; HHEX; ERBB4; AEBP1; BCL11A; TFAP2A; MEIS2; ZBED2; HMGA1; PBX3; IRF6; HOXC10; ARNT2; HOXC6
Down-regulation	203	EZH2; ELF5; PIAS1; NCOA2; ZNF432; PIR; RNF111; CDYL; TRIP4; TGS1; ARID4B; NCOA4; ATF7IP; TDRD3; SAP30; XBP1; TCF12; NCOR1; SETD2; PKNOX2; AATF; CCNC; CCNA2; PCGF2; CLOCK; NCOA1; TBL1X; GCFC2; KLF6; SAP130; TRIM33; ZNF516; ZHX2; MED17; MGA; VGLL4; MAGED1; POU2F1; HIPK1; MTDH; FHL2; RBPMS; BRCA2; IRF4; RNF138; NKRF; NFYA; MLLT10; NFIL3; ZKSCAN5; TRIM27; DPF2; PMF1; ZFHX3; TLE4; RYBP; CHD9; CNOT1; MED13; MSX1; ZMYND11; CREB3L2; YAP1; TOX; CENPF; STAT5B; MMS19; HEY1; IL16; TMF1; HOXA11; JUND; CDC5L; TCF7L2; E2F8; HIVEP1; TP63; STAT1; KAT7; NFE2L1; ZNF32; NPAT; RNF4; MYC; ECD; MED1; MBD2; CRY1; SMARCA2; RCOR1; ASXL1; ZNF263; TRIM24; SMARCC1; TOB1; KMT2A; SMAD3; HLF; DDIT3; PPRC1; TAF1D; ELF4; FOXK2; TULP4; AFF1; ETS1; TRIM32; BHLHE40; TAF5; ZNF267; FOXJ3; NCOA6; DNAJC1; CCNE1; ENO1; RERE; ZFP36L1; ZFX; CTR9; NFKB1; REST; HIPK3; EGR2; PREB; MEF2A; NR2F2; OSR2; FOXA2; PGR; ID2; ZBTB24; NFAT5; CREM; PAXBP1; WWTR1; HEY2; NUP62; SPEN; ELF1; ZEB1; KAT6B; BMI1; POU4F1; DNMT3B; TCEA1; ZBTB11; HOXB7; STAT6; BTAF1; IRF9; CEBPA; RREB1; CHD1; SPIB; LITAF; ILF2; ZNF266; KLF5; HOXB6; AHR; RNF6; CUX1; HNRNPD; FOXF2; PURA; TBX3; KLF9; FOXC1; RUNX3; BCLAF1; ADRB2; LMCD1; EGR3; HES1; SP100; BHLHE41; BIRC2; PEG3; HOXB2; SMAD2; HTATIP2; LPIN2; PSPC1; SUV39H1; SIAH2; TLE1; VPS72; JUNB; ZIC1; SMARCA1; MXI1; POU2AF1; TOX3; BRCA1; FOXN3; MAFB; ERBB2; NR2F1; PSIP1; CHD7; JARID2; TFAP2C; ID1