Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID73860	Vorinostat	GSE92742	PHH	Human	24h	10uM	EID0410

Response Information :

Types	Number	Response transcription factors
Up-regulation	154	TSC22D3; DBP; NFIL3; SMARCD2; TBP; SIX1; BRD3; STAT3; NPAT; ADRB2; RNF141; NKX2-8; ARHGAP35; RCOR1; CEBPA; SETD3; ZBTB24; YAF2; NCOR2; ECD; KDM5A; WDHD1; PPARG; MXD4; CDK9; ZNF79; HES1; SETD2; NR1H3; NFIB; ELK3; AFF1; IRX5; ENO1; HLTF; KLF9; CBX6; MEF2A; ZBTB43; CTR9; HMG20B; HABP4; RBBP5; TTF1; ZNF281; RNF4; KDM5B; BRPF1; RUNX3; THAP1; BRD4; TSC22D4; ZBTB18; KLF6; KLF12; NR3C1; NEUROG1; PURA; NFIC; LPIN2; PHF20; NUP62; PIAS1; BRIP1; EGR1; CNOT1; KMT2A; REST; KLF2; NELFB; ATF6; ZBTB11; TAL1; TAF10; HTATIP2; SMAD1; BCL3; FOXC1; MTDH; DRAP1; NFE2L1; PSIP1; EDF1; KMT5A; BMI1; CRY1; TRRAP; TMF1; FOSL1; UBP1; RARA; RUNX1; BASP1; DNAJC1; ATF3; DLX2; STAT1; BCL10; MAFF; FHL2; UBE2L3; RYBP; PIAS2; ORC2; SAP18; MED1; MED20; TLE1; GTF2A2; ZNF226; SREBF1; SUB1; ARID4B; JUNB; KDM2A; PIAS3; SMARCA2; JARID2; FOXO3; NFATC1; FOSB; SMAD2; RXRA; BBX; RUVBL2; MSX1; ERG; MTA1; PBXIP1; IKZF1; CRK; RHOA; TGFB1; HBP1; SPEN; MAFB; PTRF; RBPMS; ZEB1; WWTR1; ZIC1; ERBB2; KDM5D; HOXC6; ABL1; MXI1; NR2F2; MYB; NR1H2; AHR; SOX11; NRIP1; PBX3; ID3
Down-regulation	187	CCNA2; ATF5; APEX1; ARNT2; MEIS2; FOXM1; EZH2; TGIF1; BTF3; ZNF611; TBL1XR1; MYBL2; ZNF160; MNDA; ZNF721; SNAI2; C1QBP; TRIB3; RAD21; ZIC3; ZNF74; MZF1; LIN28A; ZNF44; ZHX2; ZNF219; KAT2A; ZFPM2; BHLHE41; SOHLH2; FOXK2; ZNF266; CBFA2T2; HMGB2; ZNF665; ZNF117; ZNF195; POLR3C; HIC2; FEV; DEK; TDP2; PFDN5; OVOL2; NR2F6; CTCF; NR0B1; POU2AF1; ST18; NPM1; ZXDC; HIRA; NANOG; MYCL; WT1; PRDM14; MYRF; ZFP64; FUBP1; MYT1; MED25; NR1H4; CTBP2; ARL2BP; CEBPG; JAK2; ILF2; CDK2; THAP7; CCDC59; ZNF124; RAN; YEATS2; ACTL6A; CBX7; CDX1; TFEB; GMNN; BCL11A; ZNF33B; HMGB1; ZNF43; HOXB5; PAX8; DDIT3; PHOX2B; RBBP8; HDAC9; TFCP2; TCF7; CIITA; PRRX1; XBP1; ZNF354A; TRIM22; BNC2; ZNF140; MYBL1; RBBP7; ZBTB38; PAX6; KLF5; ZNF652; ZNF232; TFDP1; GTF2IRD1; FOXG1; TRIM29; ZNF239; SOX13; ZNF544; THAP4; ADNP; ID1; CBX4; USP16; TEAD3; SIRT7; ZNF91; TCF4; SIX3; MLXIP; THAP10; HSF1; CHD8; PNRC1; HAND1; PTTG1; ID4; VEZF1; HMGB3; ZNF589; TEAD4; HOXC4; ZBTB20; ZBTB1; IFI16; SMARCB1; IRF8; TWIST1; CD3D; SIAH2; ZNF32; CTNNB1; YAP1; FOSL2; HOXB7; VPS72; SUPT3H; REL; SALL1; TCF21; TBX3; SSX1; ZNF12; HMBOX1; TGFB1I1; PHIP; HOXB2; MEF2C; RORA; NEUROD1; ZEB2; IRF6; TP63; ZNF264; NFAT5; JUP; AEBP1; TFAP2C; PLAGL1; PAX5; INSM1; ZNF580; SOX17; PBX1; TOX; ERBB4; ZNF512B; ARID5B; ZBED2; HEY1; ETS1; STAT5B; EMX2; PEG3; ZNF586