Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID73855	Spiramide	GSE92742	PHH	Human	24h	2.5uM	EID0410

Response Information :

Types	Number	Response transcription factors
Up-regulation	146	TCFL5; BRPF1; ZMIZ2; ITGB3BP; NCOR2; ZBTB18; IRX5; NFIC; ING2; BMI1; TAF9; RNF141; TAF12; ZNF131; ZEB2; KAT2A; PHF20; TCF12; SSBP2; SKI; PSPC1; SMAD6; CRY1; FOXJ3; BRD4; ZNF629; BRD3; SMAD3; CCNE1; FOSL1; NR2C1; HLTF; HTATIP2; KDM4C; BCOR; KAT2B; TSC22D4; STAT5A; MXI1; SOX4; BCLAF1; DDX5; CENPB; UBE2B; HDGF; ZBTB16; SETD2; HOXA10; ENO1; NFIB; ZBED1; AFF1; HES1; NUP62; HLF; TBPL1; NKX3-1; MEF2A; RXRA; ZFP36L2; RNF6; AGO2; ZNF32; HMGB1; RBL2; CBX6; NCOA6; ZMIZ1; TBL1X; KLF1; RORA; EYA2; CREBZF; SOX10; ZNF467; ZBTB25; BCL11B; NCOA4; PMS1; BRD8; SPEN; SREBF1; TLE4; CTBP2; PQBP1; RREB1; CIZ1; GATA3; RARA; ZBTB11; SAP30; SERTAD2; LYL1; KLF2; NCOA2; BLM; LPIN2; CHD1; CHD7; IKBKAP; RBM39; AR; CHD9; ZMYM2; BRD2; TRIP6; PTRF; TOX3; POLR2A; IKZF1; CRYM; BAZ1A; KLF9; SLC2A4RG; MYRF; ERG; FOXO1; TAF10; FOXO3; OLIG2; RERE; SMAD1; BBX; CUX1; RHOA; ZHX2; TWIST1; HDAC4; ATF1; PARP1; MYB; PDLIM1; NFE2; FOSL2; RFX5; TFAP2C; ARID5B; NR4A2; TOB1; ABL1; ARID4B; AHR; CRK; TRPS1; USP22; ZIC1
Down-regulation	95	ZNF606; ZNF224; TDP2; HOXD11; MNDA; ZNF223; ZNF544; ZNF175; MYBL2; ZKSCAN7; ZSCAN9; ZNF195; ZNF816; TCF7L1; NRIP1; ZNF304; ANKRD1; ZFHX2; E2F2; ZNF835; SMARCA1; ZNF426; ZNF671; GATA6; TSC22D2; MYCL; MED14; CREB3L2; HOXD3; MEIS2; PCGF3; TEAD3; HOXC11; ZNF91; EN1; FOXL2; SRF; IRF8; NAB2; IRF6; FOXM1; SOHLH2; PITX2; RLF; ZBTB20; IFI16; ZNF587; DLX2; FOXF1; THAP10; ZNF611; ZNF551; ZNF586; NANOG; SOX11; CDC5L; TCF21; HOXC4; GLI2; ZNF93; SOX13; MITF; ZNF264; PRRX1; RBFOX2; NR5A2; KAT6B; INSM1; ATF3; PEG3; NR1I2; ZNF665; NEUROD1; HMGB3; SNAI2; PLAGL1; WT1; MEIS1; ELF5; PSMC3; FOS; ZSCAN18; WWTR1; ELF3; MECOM; TRIM29; ZFPM2; SOX17; ETS2; TOX; HEY1; PBX1; NR2F2; ASCL1; FLNA