Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID73801	Mitoxantrone	GSE92742	PHH	Human	24h	2.5uM	EID0410

Response Information :

Types	Number	Response transcription factors
Up-regulation	123	BCL11B; FOSL1; POU3F1; SP110; ZNF274; STAT3; ASXL1; BATF; PRRX2; PHF20; HLTF; MMS19; MAFF; ATF6; BAZ1A; HIVEP2; RNF141; RUNX3; HOXA1; BCL10; ZMYND8; NFKB1; NKX2-1; MSX1; BRD4; PPARG; RELB; SOX4; KLF4; TCF20; CD3D; ZBTB40; MDM2; ZNF91; KLF7; FOXJ3; BRD2; HES1; LPIN2; TSC22D3; EGR4; AATF; BRPF1; CHD4; ENO1; EPAS1; CRY1; AFF1; PIAS2; RYBP; UBE2I; DRAP1; ELF1; TFCP2L1; YBX1; ZNF14; TLE1; CDYL; KLF6; EGR2; AIP; ZNF430; RNF4; ELK3; SMAD3; SERTAD2; IRF7; RUNX1; ZBTB43; MXI1; NFATC1; EN1; JUNB; SP140L; ZNF266; RB1; YWHAB; ZNF536; ZIC1; IRF1; MNT; TRIM22; TXNIP; BBX; PTTG1; KLF9; SPEN; KLF2; DLX2; TGFB1; ETS2; POLR2A; SOX9; ERBB2; AEBP1; ASCL1; TOB1; OLIG2; ID3; FOXC1; HOXB7; TSC22D2; PTRF; LOXL2; FHL2; HLF; PBX3; KDM5D; SAP30; HOXD1; CRK; CREB1; ID1; ZFP36L2; JUP; RHOA; HOXB6; ARID4B; TP63; ZBED2; SCAND1; IKZF1; TOX
Down-regulation	123	THAP11; ATF5; TCEA2; CCNA2; SSBP3; TRIB3; MYC; MED14; MEIS1; CBX5; EZH2; ECD; HIRA; TEAD3; MEIS2; BCL11A; BAZ2B; PRDM10; TBL1XR1; SUV39H1; E2F8; NFKB2; RSF1; THAP7; MED23; BRD7; IRF8; ZNF124; ETV1; TLE2; SOX13; MNDA; CRYM; SOHLH2; CUX1; ZFPM2; ZNF239; PEX2; HAND1; MGA; ZSCAN9; HSF2; SLC2A4RG; MED12; SATB2; TCF21; SUB1; ZNF195; LIN28A; FOXM1; WWP1; CDK2; GRHL2; JARID2; NR2F2; WNT4; MYCL; HOXA5; WT1; DNMT3B; ZNF512B; TFCP2; ESR1; PBX2; C1QBP; FOXG1; PITX1; PCGF2; SALL1; PBX1; HMGB2; HMBOX1; NFYC; BNC2; RBFOX2; ESRRG; ZNF12; TRPS1; PHIP; ZBTB20; ZNF304; SMARCB1; NEUROD1; TFAP2C; MAFB; ZNF652; RBPMS; ZNF107; NRIP1; FOSL2; CBFB; ISL1; HIC2; PBXIP1; HMGB3; SMARCA1; PIR; MYB; ZFP36L1; ERBB4; DDIT3; TFEC; SMARCD3; SOX17; NANOG; IRF9; FOXN3; EMX2; PPARD; ELF5; TWIST1; RORA; CITED2; HOXB2; SPDEF; ZNF586; TBX3; FLNA; MTA1; BASP1; GATA6; PEG3; STAT1