Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID73800	Mitoxantrone	GSE92742	PHH	Human	24h	10uM	EID0410

Response Information :

Types	Number	Response transcription factors
Up-regulation	118	PPARG; CNBP; MED31; ZNF131; SMARCA4; PAX8; HOXB1; PITX2; IRF1; FOXF1; NOC2L; HAND1; TBX21; HOXA7; JUNB; WWTR1; NFIC; WDR77; ZBTB7A; ZNF688; HOXA4; GFI1B; HLTF; CBX6; MBD3; HEY1; KDM4C; ZEB1; DLX5; MDM2; SOX17; XRCC6; ARNTL; YBX1; GLI3; CRTC1; SSBP3; NKX2-2; HDAC1; DDX17; NR2E1; FOSL1; BAZ1B; POU3F2; ZNF91; ZFP36L1; DLX2; NPM1; TFDP1; KLF4; EPAS1; LHX2; ENO1; FOXG1; NFIX; HMGB1; PRDM1; ARNTL2; ASCL1; MSX1; HNRNPD; ZNF423; PITX1; SOX9; PTTG1; CEBPD; SMARCA1; EDF1; GTF2IRD1; FOSB; EGR1; ZNF160; HSF1; ELK3; DRAP1; TGFB1; GATAD2A; GTF3A; FOXF2; EYA2; ZSCAN18; SIX2; KAT2B; RB1; RXRA; SNAI2; BATF3; IFI16; PEG3; SPEN; EYA1; ISL1; MNDA; KLF5; RUNX3; SOX11; RHOA; LPIN2; PLAGL1; LOXL2; ZNF586; ZFP36L2; EHF; HMGA1; MXI1; TP53; HMG20B; PAX6; ZIC1; HOXA5; FLNA; MYBL1; TRPS1; ARID5B; TXNIP; TBX3; ID3; CITED2
Down-regulation	148	CDK7; XBP1; NFIL3; TRIB3; MYC; PATZ1; ECD; TLE1; CEBPA; ZNF263; MYBL2; CCNA2; SETDB1; KDM4A; ZNF764; ZNF200; ARNT2; ZBTB3; ZSCAN16; TAF9; TOPORS; TLE4; E2F3; UBE2I; CDC5L; PHF2; TRIM32; TGS1; FOSL2; USP16; E4F1; HMGXB4; ABT1; ZNF629; UBE3A; KAT6A; ZNF267; ZNF12; C1D; FOXJ3; E2F8; TRIM27; JARID2; NFE2L1; MED23; SOX4; SP100; RNF111; BIRC2; NR3C1; TAF1D; ZNF281; NAB1; ZNF512B; THAP4; MED7; TFEC; TAF4; SOX10; MEN1; HMGB3; BRPF1; NPAT; TSC22D3; NUP62; PREB; ZNF7; SMAD1; TTF2; NR1H4; ZSCAN31; NR2F2; PRPF6; MED17; HLX; UBTF; WT1; CHD7; CTBP1; BLZF1; MXD4; NR5A2; SERTAD2; BTAF1; BCL6; ELF1; VEZF1; HIRA; ZNF394; ZBTB1; BAZ2B; GTF2A2; FOXA1; TMF1; WWP1; MED6; ZNF217; PLAGL2; PHF20; VGLL4; AHR; REST; NCOA4; HOXB7; NR1H3; TAF7; SP140L; THAP10; SMARCC2; TRIM22; PCGF3; POU2AF1; NRBF2; BHLHE40; ATF1; ZNF551; ZNF189; MEF2A; IRF7; SPIB; TCF7L1; STAT6; RARA; IKBKAP; SMAD2; CEBPZ; CRYM; MAF; SMAD3; OSR2; RREB1; MAGED1; ERG; MYB; TCF4; TSC22D1; NFE2L3; FOXO1; NRIP1; INSR; ZNF146; IRF8; GATA6; MTA1; ZNF652; ARID4B; TOB1; IKZF1