Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID73793	Aminopurvalanol-a	GSE92742	PHH	Human	24h	12.5uM	EID0410

Response Information :

Types	Number	Response transcription factors
Up-regulation	269	E2F2; ETV1; ZNF711; ZIC3; NHLH2; NFKBIB; HOXB8; KLF15; MAPK8IP1; GMEB1; RRN3; TSC22D3; CCNT1; ZNF507; L3MBTL1; ZNF589; ATOH1; ZBTB39; PRDM2; POU2F1; SCRT1; BAZ2A; ZBTB48; ZBTB16; ZNF215; MTA2; NEUROD1; ZNF778; CDX4; CTBP2; CHD2; MYT1; FOXJ3; EZH1; MYCN; SOX2; THRA; DCC; ACTL6B; WNT4; KAT6A; CBX7; ZNF814; VENTX; ZNF667; HOXB9; ZNF93; KLF7; ZNF362; AFF3; NHLH1; ZBTB17; GTF2I; UTF1; RERE; ALX4; GRHL2; FUBP1; SOX11; NEUROG2; TULP2; BNC1; KLF13; LHX5; POU5F1B; ARID1A; ZNF343; LHX1; WHSC1L1; HSF4; TDRD3; BCL11A; HOXB1; EN2; SNAPC4; ZNF551; BNC2; E4F1; TCF21; LIN28A; MED25; ZNF701; ZNF682; NRL; HIF3A; AR; TULP1; PRDM12; BCL6; ZNF426; FOXH1; AFF2; GLI3; TLX2; ZNF131; TP73; BACH2; CDIP1; HOXB6; ZNF506; NANOG; OVOL1; ZNF580; FHL2; HOXB5; PAXBP1; RFXAP; PIAS4; RARG; ZMIZ1; TFDP2; FOXI1; ZNF587; CIITA; SOX21; ZSCAN9; ZBTB20; ZNF675; HDAC9; IRX5; PRDM5; RSF1; TRAK1; HIPK2; GFI1; ZNF835; DACH1; BASP1; TRIM32; SOX13; CITED1; ZFPM2; ZNF34; TCF7L1; DBP; VGLL1; ZNF248; MBD4; SMARCC2; ZNF556; ZNF671; NOC2L; SALL1; HDAC5; PLAG1; DMTF1; GLI2; ING3; ERBB4; ZBTB44; FOXO4; CREB5; EP300; DLX2; CSDC2; NKX3-2; PPARD; YBX2; ZNF816; NR1H3; HAND1; LHX6; ZNF304; BRF2; ZNF473; E2F5; HMGA2; HOXB2; PIAS3; NFATC4; SALL2; ZNF611; INSM1; ZNF14; TCF4; FOXO3; TBL1XR1; CALCOCO1; SAP18; ZNF175; CEBPZ; MDM2; PAX6; CDK8; TGFB1I1; ZNF83; LZTR1; ZNF264; HMGB3; BCOR; SOX17; ATN1; RBFOX2; CHD7; MEF2C; ASCL1; ZNF43; PBX1; IRF6; TFEB; ZNF7; PIAS1; ZBTB18; ZNF22; PHOX2B; ZNF423; CHD8; MAFF; SP140; HOXA1; OLIG2; PAWR; GATA6; PGR; DRAP1; HOXC8; TFCP2; SP2; ZNF44; BTG1; LOXL2; CCNH; GATA2; ZNF654; RUVBL2; CBX5; WT1; PCGF2; ZNF232; SPEN; PAX5; ZNF721; TFEC; ZNF532; MYB; HEY2; HMBOX1; CHD4; ZNF415; EYA2; MYBL1; ZNF211; IFI16; ZEB1; CEBPD; ID3; MECOM; MNDA; JUP; GATAD2A; KAT6B; BLM; ZNF91; TP53; PBX3; MTA1; RUNX3; ELK3; MXI1; SPDEF; HMG20B; ZNF586; EYA1; FOXO1; KLF6; FOSB; ID2; RFX5; MSX1
Down-regulation	261	CCNA2; THAP11; SMARCA4; ECD; CEBPA; XBP1; APEX1; ATF5; NFE2L2; ESRRA; NCOA4; SMARCD2; PDLIM1; HDAC2; HIPK1; PREB; ARL2BP; THAP7; TRIM27; CTBP1; CDK7; TRIM29; KMT5A; HABP4; EZH2; MYC; SLC2A4RG; PHF2; ATF6; BIRC2; TRAF6; MED27; DNAJC2; TAF10; ZNF32; AHR; CCDC59; PEX2; CDK9; CARM1; SMAD4; ZFHX4; ZBED1; JUND; NFYA; TRIP6; TSHZ2; RBBP4; ZNF512B; MLX; BRD3; TGIF1; DDX54; ARNTL; RUNX1; MBD2; BAZ1A; NFIL3; NFYB; C1D; SMARCC1; KDM5D; DDX5; ZNF140; SFPQ; RNF10; DEAF1; CLOCK; ZZZ3; GABPB1; MED17; USF2; HDGF; GCFC2; MED13; BAZ1B; RING1; BRD7; VGLL4; NRIP1; RORA; PNRC1; NCOR1; MNAT1; NR1I2; ELK1; RXRG; SP3; CTCF; ETS2; SP110; HNRNPD; CBFB; ZNF672; CTNNB1; ZNF189; ZMYND11; ZBTB14; ZSCAN31; MDFI; CREM; FOXA2; VEZF1; CNOT6; PBXIP1; MED7; MGA; PAX8; C1QBP; SETD3; ZNF410; ZFP69B; ZNF205; NPAS2; NFYC; CENPB; NCOA3; SP100; ELF5; NELFB; CBX3; RBBP5; NKX3-1; ARID4A; MAGED1; NCOA2; KLF2; COPS5; KLF5; KAT8; RAN; CEBPB; TBL1X; TCF12; RBM39; ZNF133; ORC2; ELF1; ZNF148; SMAD3; JAK2; ARNT; ZFP36L2; NR0B2; RHOA; MYRF; LMCD1; COPS2; NFKB1; HEY1; TGFB1; CCNE1; TFAP2C; STAT5A; ING2; PATZ1; ZBTB1; TMF1; DEK; PHIP; MED20; NPM1; NR4A2; DNAJC1; AES; ARNTL2; CSDE1; ATF2; CDK2; IKZF1; NR3C2; THAP4; NRBF2; TDP2; HLF; SOX4; HOXD1; UBE2B; PQBP1; PPARGC1A; GTF2IRD1; TLE4; DDIT3; REL; CRY1; NFE2; IKBKAP; TEAD4; CERS6; GTF3A; WWP1; BAZ2B; CREB1; ENO1; SMAD6; TRIP4; MAZ; THAP10; WWC1; RNF138; RNF14; FOSL2; TOB1; MAF; PIR; ZMYM2; RNF6; CCNC; ARID5B; ISL1; RBL2; HMGN3; NFIB; SATB2; HMGB1; ZNF84; CHD9; FLNA; IRF2; KLF11; TSC22D2; SOX10; YWHAB; NFATC1; ZIC1; PARP1; CD3D; LEF1; ZNF331; TFDP1; POU2AF1; ATF4; TGIF2; CTR9; IRF9; ERG; ZNF146; DNMT3B; TBX3; FOXF2; ATF1; LPIN2; WWTR1; HHEX; STAT5B; KLF4; NFATC3; SAP30; CALR; USP22; ETS1; BHLHE41; TRPS1; NR1H2; PSIP1; ZNF652; ERBB2; IRF8; PITX1; TOX3; ARID4B