Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID73786	Cucurbitacin-i	GSE92742	PHH	Human	24h	10uM	EID0410

Response Information :

Types	Number	Response transcription factors
Up-regulation	125	MYC; NFIL3; PPARG; FHL2; AFF1; HTATIP2; MITF; CRY1; MLX; CEBPA; FOSL1; TSC22D3; RNF10; SREBF1; TAF9; BRD3; ZBTB24; SOX4; PAX8; NCOR2; TCF12; MEF2A; ZNF337; RBPMS; ATF4; SIN3B; NELFB; MAFF; SMAD2; ARNTL; NFKB1; PPARD; FOXJ3; NFE2L1; NCOA1; ENO1; SERTAD2; LPIN2; MAFB; ELK3; AGO2; IKZF1; RELB; TBL1X; LIMD1; TRIM16; ZBTB43; NCOA2; STAT3; HIPK1; MKL2; MAFG; PRKDC; MLXIP; BMI1; IL16; HOXB7; HLTF; HOXA1; CDYL; REST; MXI1; CEBPG; PURA; RNF14; BATF3; NKX3-1; BNC2; IRF1; DLX5; ATF3; FOXO1; AES; TAF1D; ERG; HIVEP2; NR1H2; TGFB1I1; DDIT3; SOX10; RNF111; EGR2; ABL1; IFI16; OSR2; CRK; ZNF84; PHF20; ELF5; ZNF552; NFATC1; ATF1; PIR; LOXL2; HBP1; RHOA; DNMT3B; TSC22D1; RXRA; LEF1; FOXO3; NANOG; TRIM29; ZNF652; STAT6; IRF4; LITAF; FOXN3; FOSL2; NRIP1; HEY1; MSX1; NR2F6; PBX3; ID2; KLF4; ID3; FLNA; KLF6; STAT1; USP22; RFX5; SCAND1; ERBB2; KDM5D
Down-regulation	99	CCNA2; IKBKAP; SSBP3; MEIS2; ZNF112; CNOT6; NR2F1; TBL1XR1; TCF21; HOXD10; EZH2; STAT4; MNDA; THAP11; MED21; PBX2; INSM1; ZNF180; NHLH2; ACTL6B; WT1; ZNF529; HIRA; OVOL2; SMAD6; SOX9; SUMO1; HDAC1; GATA6; NEUROD1; SMARCB1; MYCBP; ISL1; THAP10; DACH1; FOXM1; PHOX2B; IRF3; ZNF12; HOXD3; SOX11; PFDN5; HOXC4; IRF8; HAND1; BCL11A; ERBB4; SMARCA1; ZNF711; USP16; FOXL2; HMGB2; PITX2; GTF2I; ZNF544; PITX1; CBX4; MYBL1; NR2F2; FOXG1; EYA1; MYRF; SLC2A4RG; PTTG1; MAX; HOXD1; JUND; MYCL; TLE4; TGFB1; FOXA1; SMAD7; TCF4; MEIS1; MEF2C; ZFPM2; ZBTB20; CALR; PAX5; EHF; CRYM; CITED2; ST18; PLAGL1; TOX3; PAX6; TFEC; MAF; HOXC6; SNAI2; TRPS1; GATA3; ARID4B; ID4; MTA1; TBX3; ARID5B; PEG3; BASP1