Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID73756	Arctigenin	GSE92742	PHH	Human	24h	2.5uM	EID0409

Response Information :

Types	Number	Response transcription factors
Up-regulation	124	ZNF576; NRBF2; RUVBL2; SREBF1; TRIM25; NR1H2; DR1; CREM; RHOA; MED1; PML; EED; CCNA2; MEF2A; STAT5B; POU2F1; ESRRA; MED6; KLF5; ETS2; MED24; TRRAP; TMF1; RNF141; NEDD8; POU4F1; TAF1D; POLR2A; ZNF787; PATZ1; PAWR; WNT4; MED23; HDAC1; NFKB1; NFX1; MBD2; NFYA; DPF2; EGR3; SMAD5; BCL6; CREB3L2; CUX1; RUNX3; MTDH; ZFHX3; FLNA; GABPB1; PURA; EYA2; BRD2; COPS2; DRAP1; NR3C2; RBPMS; PSIP1; CHD9; LPIN2; EZH2; PAX8; NFIC; BCL11B; PA2G4; RBBP4; SMARCE1; NAB1; AIP; ELF3; MSC; CENPB; MXD4; PAX5; TRIM28; KLF9; PIAS2; GTF2I; ARID1A; NPM1; FOXO1; MTF2; NR2F2; IKBKAP; HLTF; TAF6; TRIP6; HIVEP1; TRIM16; PCGF2; NFIL3; NR4A1; NFE2L1; XBP1; NKX2-1; BRD4; SPEN; EMX2; TCF12; NCOR2; KLF2; ZNF467; MYB; FOXC1; SIX2; TBL1X; ERBB2; SMAD2; JUP; ZBTB18; PTRF; CREB1; NRIP1; KAT6B; NKX3-1; MTA1; PARP1; ETS1; ID2; PITX1; KDM5D; CRK; CITED2; ESR1; BASP1
Down-regulation	136	ZNF239; DNMT1; DDIT3; ZIC3; TERF1; ARNT2; ZNF415; PBX3; ILF2; VPS72; MDM2; ZNF195; ACTL6A; ZNF500; ZNF268; ZIC1; CNOT2; ZNF93; MYBL1; PRDM1; FOXM1; ZNF43; HBP1; ZNF253; MYBL2; ZNF85; ZNF606; HOXB5; ZNF215; SUB1; ZNF91; SOX11; GMNN; SOHLH2; EN1; IRF6; LIN28A; ZNF426; CAMTA1; ESRRG; ZNF107; ZNF329; HOXB2; ST18; IRF1; BLM; SOX13; ZNF266; ZNF175; CTNNB1; THAP10; TFDP2; ZNF611; ZFPM2; YEATS4; ARID5A; SOX2; ZNF423; ZNF671; ZNF140; ZNF350; ZNF562; ZNF232; DNMT3B; ZNF354A; TRPS1; PRDM2; ZNF117; PHIP; ZNF665; ZNF160; NANOG; TBX3; SIM2; LOXL2; SALL2; MYCL; PNRC1; HMGA1; BHLHE41; ZSCAN18; JUN; ZNF217; IRF9; ZNF721; NFE2L3; NFATC3; RBM39; TCF7L1; EHF; HDAC9; SOX17; FOXF2; TOX3; ELK3; ZNF304; SKI; INSM1; ZFP36L2; SHOX2; SNAI2; DLX2; ZNF83; ELF5; ZFP36L1; RB1; MAFF; ZNF544; HMGB2; ZNF165; HOXB6; CDK2; BHLHE40; FOXG1; PAX6; TFAP2C; PBX1; GLI2; CEBPD; IKZF1; ZEB1; HEY1; ERBB4; HES1; PPARD; TBL1XR1; TCF21; ZBED2; FOXF1; TGIF1; ASCL1; ABL1; ARID5B; SOX9; ATF3; ZNF586