Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID73721	Mitoxantrone	GSE92742	PHH	Human	24h	10uM	EID0409

Response Information :

Types	Number	Response transcription factors
Up-regulation	106	EED; EGR1; HOXC6; RHOA; USF2; MED27; YBX1; PPARG; SIX1; ZMIZ2; ENO1; HLTF; RNF10; NELFB; GTF3A; TRIM24; SCMH1; ATF6; SIX2; YWHAB; TRIP6; SMARCA4; FOSB; MAGED1; KDM2A; ZNF131; IRF1; PTTG1; IRX5; CASZ1; POU3F2; YBX2; TAF10; GATA2; BRD2; ZIC1; PRRX2; WWTR1; TLE2; ZEB2; MDM2; RNF141; ID2; ZBTB43; CNBP; PEX2; HIVEP2; TSC22D4; GLI2; NCOR2; NFKB1; NPM1; ZNF226; SMARCD3; PAX8; LPIN2; HOXC10; ZNF148; CTR9; GTF2IRD1; RNF6; HDAC1; EDF1; PITX2; CHD3; CRY1; CLOCK; FHL2; EGR2; HTATIP2; KLF2; SPEN; ASH2L; MSC; PIAS2; ELK3; CENPF; HMGB1; NR3C2; ARNTL2; ETV5; REPIN1; ZNF721; GABPB1; SOX11; NKX2-2; STAT1; HIPK3; RFX5; EYA1; SMAD6; CBX6; ZMYM2; MAFB; MSX1; KLF4; NR0B1; ZMYND8; ASCL1; ID3; TGFB1; PEG3; PARP1; ERBB2; TXNIP; NR2F1
Down-regulation	151	TRIB3; XBP1; CEBPB; ARNT2; CDK7; ZNF816; MEIS2; CEBPA; MYC; ZFP36L2; DDIT3; PGR; BRD7; SETDB1; DRAP1; VPS72; IL16; ZNF552; ZNF232; NAB2; PIAS4; ZNF512B; ZNF141; MYBL2; ZIC3; TERF1; BRWD1; IRF6; BACH1; NANOG; ZNF345; CEBPG; GRHL2; PBX1; HOXA10; ZNF195; TTF2; ZNF33B; LIN28A; ZNF253; PRDM10; SP140; HHEX; IKBKAP; NR1H4; ZNF589; ID4; TDP2; ZNF273; TRPS1; NR5A2; ZNF426; CTCF; TFAP2C; KLF13; WWC1; KLF3; TAF5; VEZF1; NFE2L3; ZNF281; MED7; NCOA3; ZNF91; ST18; CTBP1; TFCP2; SOX13; CDK2; POU2AF1; ID1; ELK4; ERBB4; ZNF93; PAXBP1; ZFPM2; SOX9; ZBTB20; ZNF124; CALR; ZFP36L1; ZNF202; RREB1; PLAGL2; NPAS2; FOXO3; SUPT3H; KLF9; RBPMS; TP63; IRF8; CTBP2; RNF138; SPIB; FOXG1; PAX5; TOPORS; SSBP3; IRF2; FOXA2; TOB1; DLX5; GATA6; MED1; PHIP; MYB; HIC2; SMAD1; CEBPD; TFEB; MTA1; OSR2; CNOT3; STAT6; NFIL3; INSR; KLF5; TBL1X; ZBTB16; SSX1; TULP4; JUP; NFE2; ZNF532; CUX1; ZNF304; INSM1; TAL1; ZKSCAN1; ZNF217; TOX; EHF; WT1; FOXO1; ZBTB18; PAX6; ESR1; FOXN3; TBX3; SPDEF; PITX1; SALL1; TRIM22; MECOM; ZNF586; HOXB6; KDM5D; BASP1; MYRF; SNAI2; TCFL5