Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID73706	Cucurbitacin-i	GSE92742	PHH	Human	24h	2.5uM	EID0409

Response Information :

Types	Number	Response transcription factors
Up-regulation	113	HOXC10; PURA; SETD3; USP22; ENO1; ZBTB24; AFF1; TSC22D3; ATF3; ATF4; HOXC6; SOX4; CEBPA; LIMD1; SREBF2; NFIL3; MEF2A; EZH1; MAFF; NFE2L1; LZTS1; KAT2A; BATF3; PHF20; NELFB; FOXC1; BANP; SMARCA2; NCOA1; ZNF443; PIAS2; MYCN; RHOA; NR1H3; TRIP4; MLLT10; MSC; ZNF394; SIX2; ZIC1; DDX17; RBBP8; MSX1; CUX1; ZNF217; SOX10; SMAD1; ETS2; HMGN3; FOXD1; HEY1; NCOR1; PAX8; YWHAB; MTDH; VGLL4; SREBF1; ZNF134; KLF6; BHLHE40; CDK8; CDYL; CRY1; ZNF93; DDIT3; BCL11A; ZNF419; MED20; ZNF44; EYA2; HTATIP2; GTF3A; NFATC1; ZNF430; WHSC1; RUNX1; TSC22D1; ZKSCAN1; HIVEP1; COPS5; FOXO3; XBP1; LPIN2; IRF4; PPARGC1A; REPIN1; ZNF165; FHL2; ZBED1; ETV5; ZNF544; EYA1; CRK; NRIP1; ZNF652; CBX6; TBL1X; RBPMS; SERTAD2; LITAF; ARID4B; NKX3-1; KDM5D; IRF7; ZSCAN18; ZBTB18; TP53; ZNF551; TLE4; ZNF91; PPARD; ZNF586; IKZF1
Down-regulation	79	CCNA2; MEIS2; HIRA; PBX1; NR2F1; HOXD10; EZH2; WNT4; MED14; FOXA2; ZFPM2; SOX11; CERS4; SPDEF; CCNT1; HOXD11; NFYB; WWP1; C1QBP; IFI16; HAND1; MECP2; CHD8; BRD7; ZBTB38; TEAD1; PRRX1; SUMO1; IRF8; FOXA1; IKBKAP; CHD7; VDR; HMGB1; FOSL1; YAP1; HHEX; ERBB4; NR1I2; ARNTL2; TFAM; ID4; ACTL6A; NR5A2; PAX5; TCF21; MYBL1; NFE2L3; SOX17; ZNF232; WT1; TRIM22; PROX1; TBX3; NR4A2; AEBP1; NR0B1; HOXB6; ZBED2; DACH1; CUX2; TOX3; MEIS1; INSR; TFAP2A; ID2; ESR1; ZFP36L1; GATA3; BTG1; ID1; MTF2; CREB1; SMAD7; WWTR1; PEG3; CITED2; MAFB; BASP1