Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID73705	Cucurbitacin-i	GSE92742	PHH	Human	24h	10uM	EID0409

Response Information :

Types	Number	Response transcription factors
Up-regulation	180	EGR1; BRD3; USP22; FOXJ3; SMAD3; AFF1; NUP62; SETD3; TAF1D; BRPF1; VGLL4; MYC; PPARG; ZBTB24; FOSL1; RHOA; PHF20; USF2; ENO1; NFKB1; TSC22D3; CEBPA; HTATIP2; HR; NFIB; RNF10; SOX4; MLX; RARA; SNW1; PMF1; EDF1; SCMH1; NRBF2; NELFB; CREB3; ZFP64; ARNTL; STAT3; FOXC1; MKL2; DNAJC1; MSX1; NFIC; NFIL3; SIX2; RNF141; ZZZ3; MSC; DEAF1; SMAD2; TSC22D1; TSC22D4; TRRAP; CBX6; ZNF267; BMI1; ATF4; BATF; CENPB; ZNF189; BHLHE40; ATF3; BATF3; SMAD1; NRIP1; FLNA; SMARCA2; DPF2; TBL1X; NKX3-1; NFE2L1; RBPMS; PURA; BASP1; ATF7IP; KAT7; SIX1; RBM14; NCOR1; TRIM32; ZBTB11; ELF3; DRAP1; FOSL2; KLF2; KLF9; BCL10; MNT; SREBF1; ZMIZ2; MEF2A; KDM2A; BAZ1B; YWHAB; ETS2; REST; KAT8; SP100; STAT6; ATF1; CTBP1; MAFB; TRIM16; TLE1; FOXO3; SP110; ZHX3; CLOCK; CRY1; XBP1; YBX1; RNF111; CUX1; CREB5; HLTF; BCL6; SERTAD2; UBE2L3; SMARCA4; NR1D2; SAP30; RNF6; CTR9; LPIN2; ABL1; BAZ1A; MBD2; MED13; HDAC1; MAFF; ZFHX3; CRK; SUB1; PAX8; CBFB; SOX9; TOB1; MAGED1; RXRA; TRIM29; HIVEP1; AHR; ELF4; NCOR2; FOXD1; CHD9; CDYL; AES; ELF1; MEOX1; SOX10; MNDA; STAT1; ELK3; IKZF1; ERG; BCL3; CREB3L1; PTRF; EGR2; ZNF217; PARP1; ID2; MEOX2; TWIST1; TP53; HMGA1; SCAND1; MECOM; CREB1; LITAF; KLF5; KLF6; NR2F6; PPARD; PITX1; SPEN; NR2F2; ARID4B
Down-regulation	161	MEIS2; HOXA5; CCNA2; FOXO4; HOXB5; HOXA2; HOXA4; AEBP1; RAD21; EZH2; SALL2; FOXM1; ZNF711; PFDN5; SOX3; ZNF345; HSF1; MAK; ZIC3; PTTG1; ZNF623; ZFPM2; NANOG; SUMO1; DCC; ZNF682; GATA1; CSDC2; ZNF500; PRRX1; TERF1; NHLH1; FOXH1; ZNF816; TCF21; ZNF589; EN2; ZNF219; SOX13; PRDM2; SMARCB1; NHLH2; HOXB9; E2F4; L3MBTL1; CNOT6; SOX2; ZNF573; ZNF215; ZNF10; HOXD13; HOXD11; PBX3; ENY2; INSM1; NFE2L3; ST18; FOXK2; SOX11; HIC2; FOXJ1; ZNF665; PGR; ZNF180; ZNF529; HOXC4; ZNF835; CNBP; BCL11A; CBX7; ZNF34; MYBL2; EGR3; HIRA; HDAC5; WT1; ERBB4; ID4; CBX4; HOXB6; DDX5; PNRC1; ZNF135; PROX1; ARL2BP; HMGB2; ZNF426; ZNF544; NEUROD1; LIN28A; ZBED2; SOX17; TBL1XR1; PAX6; NR2F1; DDX17; ZNF611; ZBTB20; WWP1; PSMC3; SOHLH2; TCEA1; FOXA2; ZNF264; MZF1; ZNF12; ZNF580; HOXB2; UBE3A; IRF1; ZNF273; ZNF551; FOXF2; E2F5; HEY2; SMARCA1; PCGF3; NR4A2; KLF1; ZNF33B; TULP3; FUBP1; TFCP2; HHEX; DLX2; FOXL2; ZSCAN18; MYB; IFI16; SNAI2; FOXF1; TOX; IRF6; ZNF22; NR2C1; ZNF415; ZNF44; ZNF165; JUND; JARID2; PLAGL1; KAT6B; ZNF304; ZNF43; SMAD6; EYA1; PEG3; DACH1; LEF1; SPDEF; FOS; TRPS1; MTF2; HOXB7; ID3; ASCL1; ZNF331; ZNF586; HEY1; ID1; E2F2