Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID73645	Mitoxantrone	GSE92742	PHH	Human	24h	10uM	EID0408

Response Information :

Types	Number	Response transcription factors
Up-regulation	76	MED17; DRAP1; MED27; PSMC3IP; IRF1; NFIX; HINFP; CREB1; ZNF177; ZNF423; TFEC; PPARG; MAFF; ZBTB43; BCL10; KLF7; CBX7; CCNT1; FOSB; PRRX2; ZNF562; NFKBIB; TSC22D2; MDM2; GATAD2A; MECP2; ATF3; SMARCA4; SIX2; BRD2; MYCL; BAZ2A; MEF2A; CDK9; BBX; ZNF93; MXI1; FOSL1; SOX2; BRD4; PSMC3; KLF13; ZBTB18; KAT2B; KLF10; HTATIP2; MYCBP; NR4A2; KLF4; YWHAB; MECOM; HMGN3; TCF21; ID3; HDAC9; EMX2; ERBB4; TP53; ZBED2; ZFPM2; BCL3; CITED2; ZNF91; YBX3; ID4; ZSCAN18; SERTAD2; SATB2; ARID4B; ASCL1; TRIP6; ZMYM2; BASP1; HES1; PBX3; TOX3
Down-regulation	80	MYC; CCNA2; CEBPB; XBP1; ECD; CEBPA; EZH2; ZBED4; CTCF; TBX3; ZBED1; ZNF512B; ATF2; SREBF1; PGR; PATZ1; CALR; PRKDC; POU2AF1; NCOR1; ZFP36L2; NFYA; RORA; ZFHX3; CNOT3; VGLL4; TCEA1; UBE2I; MED23; TFAP2C; JUND; NCOA2; SLC2A4RG; PEX2; CEBPD; NR5A2; NFKB1; TWIST1; SMAD2; DDX17; SNAI2; TLE4; FOXO1; ZNF165; RBBP4; CREM; NRIP1; ZFP36L1; HMGB2; SOX10; IRF6; RYBP; ZNF410; FLNA; MEIS1; MITF; NCOA4; EGR3; NPAS2; SMAD1; HLF; ELF1; ELF5; LEF1; SOX4; MBD2; SMARCA2; TRPS1; HEY1; FOXN3; IRF4; NR1H2; ARID5B; PBX1; MAF; SOX9; IFI16; ERBB2; MTA1; TFAP2A