Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID73608 Silibinin GSE92742 HA1E Human 6h 20uM EID0403
Types Number Response transcription factors
Up-regulation 75 HDAC1; TBP; PATZ1; HOXC6; HDAC6; EGR2; CREG1; C1QBP; FOXJ3; USF2; ZNF672; MSX1; SMARCD2; DDX5; NCOA4; FHL2; MLX; HOXB7; PUF60; SMARCE1; BATF3; PTTG1; BCLAF1; SFPQ; SNW1; MED23; IKZF1; RAN; ENO1; HLTF; XRCC6; ATF4; HMGA1; YBX1; STAT5B; PSIP1; ELF1; BRD2; SOX10; HSF2; ELK1; TGS1; TSC22D3; ZEB2; CEBPG; ATF3; ID2; BAZ1A; SFMBT1; UBTF; SNIP1; HMG20A; ADNP2; RBBP4; ORC2; BAZ1B; UIMC1; KDM4A; APEX1; POU4F1; STAT5A; IKZF5; NFKB1; ECD; NEDD8; TBPL1; KAT7; PURA; CTNNB1; KAT8; NPM1; PSMD9; ZNF16; RCOR1; MITF
Down-regulation 39 RB1; HOXD1; SNAI1; ZMIZ1; ZNF532; ZNF415; CEBPD; CUX2; SOX2; PBX1; ETS1; ZNF665; CDIP1; IRF9; TCEA2; E4F1; BARX1; ATF5; HIF1A; ZNF141; BNC1; PBX3; ZNF117; PRDM14; PRDM1; SPDEF; NCOA3; VPS72; PRRX1; RARG; NFATC4; NHLH1; CREB3L2; ING4; BCL11A; NR2F6; TCF7L1; NFKB2; PRDM5