Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID73519 1,2-propylene-glycol GSE92742 HA1E Human 24h 10uM EID0399
Types Number Response transcription factors
Up-regulation 85 KDM5D; AIP; TADA3; PCGF2; AATF; ZFY; NRIP1; PATZ1; ZHX2; EDF1; CDK9; MED24; SMARCB1; PA2G4; BCLAF1; INSR; TFAM; ATF3; RBBP4; SREBF2; KAT5; MLXIP; CSDE1; SOX4; EMX2; MAZ; ZFHX4; TTF1; KLF6; RFX5; NELFB; ATF4; POU2F1; TP53; CNOT2; SF1; BTF3; PMF1; BATF3; MMS19; GTF2F1; ZMYM2; SSRP1; ZNF219; BACH2; HLTF; RBPJ; HOXD11; MAF; PFDN5; PUF60; RBBP8; PSPC1; BIRC2; BRD2; ZFPM2; YBX3; RBM39; ESRRG; HMGB1; YWHAB; HOXC6; MYB; DMTF1; SMAD1; ZNF423; TCF7L2; BTG1; SCAND1; PTTG1; SALL2; JUND; MTA1; CARHSP1; IKBKAP; PCBD1; NR4A2; WT1; HMG20B; CITED2; IKZF1; IRF6; MYCL; ARID1A; TBL1X
Down-regulation 79 KDM5C; CREBL2; BRIP1; ZFX; LEF1; AHR; CRYM; CBFA2T2; FOXF2; HOXB2; MED14; TDP2; ACTL6A; IRF2; SUPT7L; MYBL1; TFAP2C; TFCP2L1; NFE2; SMAD6; HOXA1; PPARGC1A; ZNF189; TFAP2A; KLF5; PITX2; MECOM; ST18; ZNF175; STAT3; NKX2-1; PRRX1; YEATS2; TGFB1; LOXL2; ZNF512B; USP22; MDM2; SAP30; CBX7; E2F8; TRIM22; EGR2; TAF4; FOSL2; ZNF93; EYA1; ZIC1; PNRC1; TBX3; ZNF217; ZNF160; NR2F1; SOX9; ZNF331; DDX17; ZEB1; NPAS2; SNAI2; MEIS1; BASP1; PEG3; EGR3; MEIS2; ADNP; ZEB2; ZNF586; ETS2; HOXB6; TRPS1; CCNE1; DLX5; CEBPB; BHLHE41; SMARCA2; MKL2; TWIST1; ID4; TXNIP