Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID73469	Mitoxantrone	GSE92742	HA1E	Human	6h	10uM	EID0398

Response Information :

Types	Number	Response transcription factors
Up-regulation	112	AEBP1; TDP2; ZNF117; GRHL2; ENY2; CDX1; HOXD1; CCNH; SPI1; ZNF532; ZNF33B; CBFA2T3; SPDEF; ST18; ZNF415; IRF6; INSM1; SRY; TCF12; TULP4; MYT1; CNBP; CSDE1; BRD7; ZNF215; HOXB13; CDIP1; JUP; ZNF219; NHLH2; MED14; DNAJC1; RARG; ZNF83; CERS6; KAT2B; ZNF665; CREBL2; SUPT3H; PRDM14; ZSCAN18; MXD4; DACH1; CUX1; ATN1; PAWR; KLF13; ZNF711; BAZ2B; ING4; INSR; TCF21; PAX5; CUX2; PHIP; RAD21; ZNF43; ZSCAN31; BCL11A; CDYL; CAMTA1; HSF1; ZNF93; MYRF; MED20; DMTF1; SREBF1; EHF; NFE2L3; PSMC3; EMX2; YBX1; AES; CBFA2T2; MYCL; HDAC9; ZNF544; NKX3-2; HOXD3; TRIB3; ZNF195; ZNF606; ZBED2; ZFPM2; HMGN3; ZNF589; TLE2; SIX3; CTBP2; TCEB2; MECOM; MTDH; MBD2; E2F5; ID4; ARNT2; ZNF91; ATF5; RFX5; HMGA1; ZBTB20; SOX10; PBX3; STAT1; ZNF467; ZEB1; TOX3; NANOG; MTA1; SOX11; IKZF1; ZNF423
Down-regulation	264	NFKBIA; MYC; FOSL1; FHL2; HOXA5; SUV39H1; FOXO3; HOXA10; BHLHE40; CCNA2; NUP62; CTR9; JUN; NFIL3; CDK7; ASXL1; SMAD3; GABPB1; MAX; TTF1; FOSL2; FOXJ3; ADNP; KAT7; MSC; ID2; NRBF2; FOXD1; MAFF; CRK; SALL1; HOXA1; ZNF131; EGR3; NCOA4; ING3; CITED2; ZNF410; PITX2; ZNF473; RNF4; KAT6A; ZFP64; CEBPB; SUZ12; ZNF200; TBP; BRPF1; SCAND1; POLR2A; PAX8; KDM5B; MTF2; MNT; PLAGL2; ZFP36L1; ZNF267; HOXA11; ZBTB1; MED6; EED; TRAF6; VGLL4; PHF8; NKX3-1; ZNF394; GATAD2A; ING2; POLR3F; REST; SMAD7; TRIM32; MED7; HES1; SNIP1; BCL3; JUNB; MED1; CHD8; HOXA7; PATZ1; MSX1; ZNF202; ZNF408; HLF; ZNF45; RBL1; ZNF629; STAT5A; ZNF576; ZBTB24; RELB; RARA; NR3C1; ING1; SIX1; MKL1; BRD8; CENPB; MED13; UBE3A; ID3; FOXO1; DNAJC2; DEAF1; MAGED1; NPAT; NELFB; HMGXB4; MTF1; ADNP2; THAP1; NFRKB; TRRAP; AHR; NR2F2; SIX2; CCDC59; ZNF672; TRIM16; ELF2; BCL10; ERF; RXRA; TAF1D; ZNF217; ELF4; RLF; IKBKAP; TMF1; PPRC1; CRY1; DPF2; ZNF263; TSC22D4; HIVEP1; ZNF593; ZNF574; TRIP6; MED17; XBP1; FOXJ2; BATF3; RCOR1; BATF; ZBTB18; NEDD8; FOXC1; EGR2; ZKSCAN5; RNF111; APEX1; GTF2IRD1; FOXL2; SIRT7; SFMBT1; JARID2; IRF2; SMARCD3; TEAD1; SP2; NCOR2; IFI16; MAFB; BRD3; JUND; RUVBL2; CIZ1; ZNF212; BTG1; ELF3; TFE3; KDM2A; ZEB2; KLF2; STAT6; ARNTL2; BAZ1A; DAXX; BCOR; SMARCA2; KLF12; CEBPZ; NR3C2; SPEN; BASP1; GATA3; NRIP1; SIAH2; ZNF14; RUNX3; SOX9; LPIN2; RELA; ZBTB43; FLNA; PLAG1; BAZ1B; CREB3L1; PCGF1; SAP30; CCNE1; TRIM29; HOXB6; TOPORS; SAFB2; BLM; PPARGC1A; ELF1; CHD1; ATF7IP; CITED1; NR1H2; RBM14; IRF3; HIVEP2; SMAD6; FOSB; HOXB7; BMI1; AFF1; DNMT3B; ETV5; FOXG1; HIC2; WWTR1; NFIB; PITX1; ZBTB38; ZNF266; TLE4; KLF10; ZNF430; SOX4; DDIT3; HSF2; CTBP1; TBX3; CD3D; FOS; TBPL1; KLF5; PCGF2; RNF6; CREB3L2; SERTAD2; ARID5B; TRIM28; TBL1X; BHLHE41; ZBTB16; VEZF1; RUNX1; ELK3; TSC22D3; HOXC10; TGIF1; ARID4B; ZNF468; TLE1; HOXC6; TSC22D1; HOXB2; KDM5D