Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID73339	Tizanidine	GSE92742	HA1E	Human	6h	10uM	EID0397

Response Information :

Types	Number	Response transcription factors
Up-regulation	149	ZNF589; ZNF654; IRF6; ZNF264; PIAS4; KLF13; NR2C1; GON4L; PPARD; ZNF91; CERS6; ZBTB16; SPI1; PRDM10; EP300; TCF7L2; MKL1; ZNF43; HMBOX1; ZNF304; FOXA1; HDAC4; ZNF606; SPDEF; BRD7; TBX3; EHMT2; ZNF500; CUX1; MLXIP; KAT6B; ZNF586; TRIM28; ZKSCAN4; SIAH2; KAT2B; ERBB4; YEATS2; RREB1; ZNF544; SOX12; CBX7; EYA1; ZMYND8; AR; CTBP2; GATA2; ZNF8; FOXG1; PATZ1; CHD8; INSR; FOS; HMGA1; SMARCA4; TRIB3; ZNF268; CUX2; ZNF239; ZNF93; SALL2; TGFB1I1; DAXX; ZNF444; ZNF426; ZNF671; HMGXB4; ARID1A; IRF9; ZNF573; MEIS2; ZFPM2; SOX2; ZNF467; ZNF134; BRD4; ZNF587; BCL11A; NANOG; ZNF551; PHIP; ISL1; NFKBIB; ZNF131; JUP; ZNF580; TULP3; ZBED4; EWSR1; MNDA; ZNF423; CREB5; MTA1; WWC1; CHD9; CBX4; ZZZ3; ARNT2; ZNF232; ZHX2; REL; NFIB; CBFA2T3; ESR1; URI1; CNOT3; ZNF419; TFAP2C; TCF21; STAT4; CBX6; ZNF512B; GRHL2; NR2F2; FOXF1; BNC2; STAT1; MYCL; IKZF1; FOXN3; GTF3A; TSC22D3; ZNF593; ZSCAN31; RBPMS; LIN28A; APEX1; SALL1; EMX2; THAP11; SP140L; CITED2; PEG3; ZNF140; NR1H2; ATF5; GATA6; FOXO3; ZMYM2; AEBP1; WT1; MECOM; HOXB2; ELK3; YBX3; FOXF2; KDM5D; NR2F6; DACH1
Down-regulation	106	EZH2; FOSL1; BRCA1; BMI1; NCOA6; LPIN2; BRD8; JUNB; NFIL3; ORC2; ELK1; HOXB9; TAF1D; TSC22D2; ZBTB38; ATF6; RHOA; ECD; FOXJ3; FOXI1; BTG1; ELF1; ATF1; POU4F1; NAB1; ID2; RBBP4; TP53; CDX2; DLX5; TCF4; RB1; ZBTB1; PBX3; ERG; FOXD1; ELF3; CTR9; POU2AF1; XBP1; MBD2; HSBP1; NCOA1; MED1; HTATIP2; CALR; EED; BAZ1A; HLTF; MAFF; NPAT; HMGA2; UBE2B; TAF4; KLF10; LEF1; ID1; SMARCA2; MKL2; HOXA1; SMAD7; NR1D2; IRF2; CHD1; NFE2L2; HEY1; SOX4; RUNX1; ETS2; ING3; HMGB3; TAF10; NR2F1; MAF; DLX2; STAT3; NRBF2; SMAD3; ATF3; STAT5A; SMAD5; ING2; NR1H3; DDIT3; SOX9; NR4A2; SMAD1; PURA; CCNE1; KLF9; NR0B1; TFDP2; SSX1; HIVEP2; TSC22D1; MNAT1; MSX1; NCOA2; BIRC2; ELF5; EGR2; VPS72; TOB1; SSBP2; TWIST1; EGR3