Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID73309	Mitoxantrone	GSE92742	HA1E	Human	6h	10uM	EID0397

Response Information :

Types	Number	Response transcription factors
Up-regulation	80	CEBPD; NHLH2; FOXA1; AR; HIF3A; ERBB4; CERS6; SPI1; MEOX2; ZFPM2; SOX11; HAND1; TCF21; JUP; GATA2; FOS; ZNF536; KAT2B; SPDEF; FOXF1; IRF8; PBXIP1; RB1; MXD4; HMGA1; IFI16; NR1H4; SUMO1; ZNF226; ESRRG; NR5A2; SRCAP; ZSCAN31; ZNF467; TGFB1I1; NFKBIB; HSBP1; ZNF532; MTA1; REPIN1; MNDA; PAWR; CREB1; ZNF274; INSR; HMGB3; SP140L; GTF3A; L3MBTL1; MYCL; GRHL2; TULP3; HDAC3; TXNIP; CERS4; PBX1; NR4A2; HOXD1; ZNF232; SALL2; DACH1; HDAC9; AEBP1; RNF10; CBFA2T3; CNBP; IKZF1; ARNT2; EHF; TRIB3; RBFOX2; MECOM; ZSCAN18; STAT1; ATF5; ATF4; THAP10; YBX3; PEG3; MEIS2
Down-regulation	256	FOSL1; MYC; NFKBIA; CCNA2; IKBKAP; SUV39H1; NUP62; FHL2; EZH2; ZNF443; BHLHE40; KLF7; TSC22D2; NFIL3; DLX5; FOXJ3; SMAD7; CDK7; CRK; SUZ12; MAFF; TAF1D; ASXL1; NCOA6; ZBTB1; MLX; ING1; PLAGL2; JUNB; HSF2; EED; ZBTB24; SNIP1; ZNF267; ID2; HOXA1; USP22; ZFP36L2; TRAF6; HIC2; GABPB1; ZNF222; ZFP64; ZNF410; JUN; BMI1; ZNF281; ATF1; NPAT; TBP; MAFG; BTG1; ZKSCAN1; FOXO1; VGLL4; VDR; CHAF1B; PNRC1; FOXK2; ZNF146; HMGA2; ZNF217; SIX2; KDM2A; ZBTB18; ZNF672; SOX4; FOXD1; HOXB7; HMBOX1; FOXA2; TAF5; SATB2; BTF3; PGR; NFKB1; RBBP4; ARNTL; HOXB6; PPRC1; SAP30; CHD1; ADNP; TBL1XR1; NCOA4; SERTAD2; KLF12; TAF4; ZNF629; DDX5; HES1; ZNF430; ZBTB38; GMNN; RELB; DEAF1; RARB; XBP1; JUND; CHD7; PRRX2; ALX1; KLF2; MEF2A; IRF7; HOXA5; MED1; RBM14; SHOX2; MYCN; SMAD3; PIAS2; CITED1; AGO2; TGS1; MED13; TFAP2A; JAK2; SMAD1; MKL2; GTF2IRD1; NFYA; ZNF473; BACH1; PAX8; CENPF; FOXC1; HTATIP2; PATZ1; KLF6; HOXD10; NLK; RORA; CTR9; ZEB2; NKX3-1; KAT6A; ZIC1; ZFHX4; BRPF1; TRIM29; DNMT3B; BCL10; IRX4; BLM; VEZF1; EGR2; ANKRD1; RUNX3; KMT2A; TRIP11; BCOR; KAT7; BATF3; ZNF574; SOX13; KLF9; TBX3; ZNF282; IRF2; KDM5B; IFNB1; ERG; PCGF2; SNW1; IRF4; SMARCA2; TFAP2C; HOXA11; ZBTB25; LITAF; ELF4; CCNE1; PURA; BACH2; ZNF131; POU2AF1; ATF7IP; LZTS1; HMGXB4; MITF; NCOA1; NRBF2; CARM1; ZNF266; ZNF148; MNT; HIVEP2; NCOA2; ATF3; HOXA10; HOXC10; NCOR2; DDX17; MED17; NR3C1; ASH2L; DLX4; CCDC59; MED6; PKNOX1; EGR1; SOX9; ID1; NFRKB; ZFP36L1; TOB1; JARID2; SNAI2; KLF4; MED15; TBPL1; MYBL1; HEY1; ZNF394; TAF1; TGIF1; EGR3; PAX5; BRD3; HOXC6; TLE1; ERF; HIVEP1; ZNF652; CRY1; EP400; LEF1; PLAG1; KLF5; DLX2; NRIP1; ARID5B; SMARCA5; DDIT3; AHR; CBX6; MAFB; TSC22D1; RUNX1; SPEN; MTF2; ELF5; LMCD1; STAT3; TEAD1; TWIST1; NFIB; ID4; FOSL2; NFAT5; FOXO3; KDM5A; BHLHE41; SSBP2; TRPS1