Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID73072 Iodoacetic-acid GSE92742 HA1E Human 6h 10uM EID0396
Types Number Response transcription factors
Up-regulation 87 HES1; EGR1; DDIT3; JUN; FOSB; HBP1; NAB2; TSC22D1; NFIL3; BRD2; EGR3; NR4A1; MXD1; FOSL1; SOX4; ETS1; AFF4; ZMYND8; NRIP1; IKZF5; CEBPB; BBX; BHLHE40; ATF3; RLF; BTG1; MAFG; ATF4; ELF1; DBP; MDM2; NR2F2; KLF6; ZNF91; CCDC59; KLF13; ZMYM2; CHD1; XBP1; CNOT3; PSPC1; IRF1; DNAJC1; HOXD1; TAL1; IRX5; KLF10; FOXG1; PBX2; TRIP6; FOXC1; KLF2; HMGA1; TBX3; KLF4; SIX1; TWIST1; KLF5; FOSL2; ID2; RYBP; INSM1; JUNB; SERTAD2; HMGB2; MTA1; ZSCAN18; BAZ2B; RBPMS; MSX1; MAFB; TOB1; ZNF587; ERG; RREB1; BCL3; ESR1; NR2C1; ZNF586; SAP30; JUND; FOXD1; HOXC6; CTBP2; MNDA; IKZF1; MTF2
Down-regulation 30 TFCP2; ARL2BP; SMARCD2; GTF2A2; TRAK1; BACH2; CERS4; EED; MKL2; PSMC3; HHEX; PRPF6; TBP; IRF9; TRIB3; YWHAB; TCF4; PCGF2; SALL2; MEIS1; SMARCA1; WWC1; SOX11; ZNF589; MAGED1; ZBTB16; MYRF; ZBTB18; TRIM22; TCFL5