Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID72939	Hyoscyamine	GSE92742	SKB	Human	24h	10uM	EID0392

Response Information :

Types	Number	Response transcription factors
Up-regulation	199	TOB1; SCRT1; TRPS1; CBFA2T2; MLLT1; SSX1; LHX3; ELF4; ZNF74; POU4F3; ACTL6A; EN1; CDK2; GFI1B; VGLL1; CBX4; HIC2; POLR3C; ZNF235; BCL11A; ATOH1; ZNF232; PAX6; ETV1; ZNF816; INSM1; RARG; TP73; THAP7; RING1; VENTX; HOXD13; ZXDC; E4F1; BNC1; TAF5L; ZNF331; TBX21; KLF11; PCGF1; BARX1; ACTL6B; FOXA2; NEUROG2; ZNF562; HOXD11; CDX1; GATA1; ABT1; NFATC4; KDM5C; HMGB2; HOXB1; CNOT3; CCNH; PFDN5; ARID3B; CAPN15; ZNF350; NR1H4; MED15; TCF20; KAT2B; DLX5; MEIS2; SIRT7; ERBB4; ZNF394; MED17; ATN1; SOX15; CCNT1; ID4; OLIG2; RAD21; BCL11B; ZNF215; TULP3; ZNF467; ZMIZ1; PRDM14; ZNF223; ZSCAN18; CREB3; MYRF; NR0B1; SOX5; SOX9; ZBED2; ZNF266; HOXD1; ETV4; VEZF1; TRIB3; SOX13; OVOL1; ZNF239; NKX2-2; IRF6; HIVEP1; RORA; TSC22D4; JUN; ZNF45; UBE2B; PBX3; HOXD10; STAT4; NFE2; ZNF44; MYBL2; SP3; MXI1; PEG3; UBE2L3; CREBL2; FOXF2; RNF138; ZNF623; LITAF; TP63; ZFP36L2; NR5A2; TGIF1; NKX2-1; MKL2; MYBL1; PSMC3; HHEX; NEUROD1; KLF13; ZHX2; PHF1; ZNF148; TDP2; HOXB5; HOXC10; ZNF91; SALL1; SHOX2; FOXG1; SPDEF; RBFOX2; TFAP2C; FOS; ING4; NR1H2; DLX2; TFAP2A; FOXE1; DDIT3; MYCL; DEK; DNMT1; FOXK2; VPS72; CALR; HMGB1; WT1; IFI16; NPAT; TCF21; ZNF43; CREB1; GMNN; SALL2; GATA6; ARNT2; KLF1; ST18; ZBTB16; ZNF573; SMAD7; CITED1; PAX5; HES1; ZNF544; FOXJ1; HDAC9; ZNF611; ZNF264; ZNF329; HOXB2; ZFPM2; ATF3; EYA1; CD3D; PITX1; LEF1; PBX1; ARID5B; KLF10; HOXB6; TXNIP; CTBP2; NR4A2; ESR1; ID1; THAP11
Down-regulation	223	USP22; NR2F6; FHL2; STAT1; CRK; USF2; NCOR2; SSRP1; PUF60; YWHAB; SREBF1; ECD; NFKBIA; DNMT3B; RHOA; NELFB; RUVBL2; PCGF2; TSC22D3; EDF1; FOSL1; SMARCA5; DPF2; NFKB1; SIAH2; PSPC1; FLNA; RBM14; PHF2; TBP; REPIN1; PRPF6; RELB; ZNF146; KLF7; ASH2L; CUX1; SETD3; POLR2A; RNF10; ARNT; PHF8; ELF1; PARP1; ZBTB11; ZNF189; NUP62; HIPK3; ZHX3; SMARCE1; TP53; ELK1; TERF2; NR2C1; FOSL2; ZNF302; ZNF587; TAF1D; HOXB7; BASP1; SCAND1; MED6; ING1; ATF5; ZMYND8; PKNOX1; ZNF614; HDAC5; ZFP64; ERCC2; TRIM28; SCMH1; SNW1; TTF1; MDM2; LMCD1; KAT7; SP100; ORC2; NCOA6; SAP18; MYOD1; NSD1; MED1; MLXIPL; MEF2C; RFC1; KLF6; KMT2B; UBE2I; ZMIZ2; BCL6; NFE2L1; BRF2; EBF2; DDX54; TSHZ2; HSBP1; TAF10; PAXBP1; CARM1; MNT; CITED2; NCOA4; CHD3; ZBTB24; ZNF281; WHSC1; ZNF23; COPS2; AATF; PLAGL2; PIR; MAF; MLXIP; GABPA; RUNX3; KLF12; HEY2; MMS19; INSR; RARA; FOXD1; PRMT2; FOXJ3; SMAD4; HSF2; MTA1; PATZ1; ZNF536; RNF14; CXXC1; ETS2; TFDP1; TSC22D1; PURA; RUNX1; BAZ2B; ENO1; MED4; EMX2; TRAK1; RNF141; CTNNB1; FOXO4; RB1; TOX3; MNAT1; MSX1; MAX; RBPMS; SIX1; NEDD8; MBD2; TCEA2; NFIL3; MXD4; RBBP5; TCEB2; BRPF1; SND1; KLF2; CBX3; FOSB; BRD3; ATF4; UBP1; TRIP6; CBX6; TGFB1; GABPB1; CTR9; MED24; NRBF2; L3MBTL1; ASXL1; BMI1; MECOM; TCERG1; MTDH; MLLT10; NFATC1; BAZ1A; MAFG; FOXN3; ELF3; HDAC6; EGR2; ZBTB18; PIAS2; NR1H3; DNAJC1; STAT5A; SMARCA1; CHD1; ZFHX4; FLI1; HMGN3; SMAD2; SMARCA2; MAGED1; TRIM22; IRX5; HOXC6; TRIM16; SAP30; GTF3A; NKX3-1; XBP1; KDM5D; AEBP1; NR1D2; KLF4; ZEB2; HEY1; KDM5A; ELK3; NFAT5; MEF2A; SMARCD2; ERG; CREB3L1; TBPL1