Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID72806	Metolazone	GSE92742	SKB	Human	24h	10uM	EID0392

Response Information :

Types	Number	Response transcription factors
Up-regulation	81	NR1H4; HOXA4; HOXB7; NFYC; INSM1; MAFF; GCFC2; HOXC10; PEX14; LITAF; MYCL; ACTL6A; HOXC4; HOXA5; TOX3; PIR; POU4F1; THAP10; BCL11B; ZNF232; HIVEP1; GLI2; TCF3; PNRC1; BCL11A; NCOA2; TTF2; MYCN; SMAD6; ZNF7; HSF1; CERS6; RAD21; FOXM1; HOXD1; SOX13; REPIN1; MEOX1; NR3C2; CREBL2; SALL2; ZNF665; FOXD1; PAX6; TSC22D1; ZNF239; SIX3; BACH2; HEY1; SIM2; TLE4; TCF21; DACH1; ZNF264; LEF1; MKL2; FOXG1; SPDEF; TFAP2A; SAP18; HLF; VDR; FOXF2; TOX; ID3; SMAD7; POU2AF1; BHLHE41; SALL1; NANOG; HDAC9; ATF3; ZNF652; FOXF1; ZNF160; ASCL1; ZNF721; HOXC6; PEG3; MYBL1; VGLL4
Down-regulation	82	GMNN; TAF10; PRPF6; SCAND1; C1QBP; ZNF532; ZNF281; ZNF131; YWHAB; RBM39; USP21; NFKBIA; HMGB3; BCLAF1; KMT5A; SP140L; ELK3; SRCAP; LMCD1; YBX1; NCOA6; WWC1; CARM1; CHD9; PTRF; STAT1; ZBTB18; MAFG; FLNA; MDM2; EDF1; NFKB1; ZBTB16; HSF2; ZMYND8; OSR2; HSBP1; DMTF1; ZNF512B; ZNF83; BCL6; JARID2; FUBP1; UBP1; CHD7; SMARCA1; TRIP6; PMS1; BTG1; RNF10; PURA; NRBF2; CITED1; BASP1; KDM5B; BBX; HIRA; PRRX1; RBPMS; TRIM16; TP53; IRF6; CTBP2; BATF; TRIM22; MEIS1; EMX2; RFX5; HHEX; CITED2; TBL1XR1; EHF; ZBED2; MTA1; ZIC1; PBX1; TXNIP; TBPL1; SMARCD2; NR4A2; ZFPM2; NR2F2