Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID72750	Brinzolamide	GSE92742	SKB	Human	24h	10uM	EID0391

Response Information :

Types	Number	Response transcription factors
Up-regulation	212	KDM5A; ZNF711; SKI; RSF1; WHSC1L1; ASCL1; NOCT; IKZF1; KMT2D; NR0B2; NR1I2; FOXN2; PKNOX1; ZBTB44; PRMT2; ZNF292; RBL2; PAX1; TXNIP; ZNF334; TOX3; BACH1; TFCP2L1; RARB; SIM2; E2F2; ACTL6A; HOXB5; RBBP5; BANP; OVOL2; BNC2; NR4A3; TOPORS; MDM4; CSDE1; TBX1; FOXD1; SATB1; WT1; NFAT5; FEV; IFNB1; ZNF93; NPAT; FOXE1; ZNF160; UBP1; NR1D2; MNT; NEUROD1; CENPF; SSRP1; BRWD1; HOXB7; HMGA2; RELA; SUMO1; CCNT1; MEIS1; BTG1; BAZ2A; C1D; MSC; SPI1; SOX11; PRKDC; TAF1A; CHD4; BBX; KLF15; ZFY; PHF8; POU4F2; TFAP4; CNBP; HAND1; HSBP1; KLF9; NSD1; NHLH1; SMARCA1; KLF11; ZBTB38; LHX6; HIVEP3; SKIL; WNT4; SOX12; ZNF507; SMARCC2; ZNF141; JUND; NFIX; KAT8; HOXB6; EGR2; HOXB2; THRB; ZNF528; RAD21; ETS2; BCOR; NR4A2; PBX2; NKX2-2; ZNF587; ZNF148; SSBP3; GATA6; ZNF492; TFAM; SFPQ; ZNF835; ZNF302; NR1I3; NFYC; BRIP1; GATA3; ZNF257; MYCN; KLF10; KAT7; TERF2; NR1H3; SUV39H1; DDX17; IRF4; BCL11B; SERTAD2; MTDH; CBL; MAFB; MXD1; ZNF217; SOX13; HMGB2; ISL1; EGR4; TMF1; SMARCA2; ZNF721; TCFL5; DLX5; GRHL2; KDM5D; FOXN3; ZNF331; MED1; ARID1A; TGFB1; MED12; HSF2; CAPN15; RARA; RUNX3; BRD4; HLX; ADNP; TRIM25; ZNF682; INSM1; BAZ1A; GABPA; PHOX2B; RB1; IRF2; ZNF329; RBM14; KMT2A; HOXC4; MYCL; DLX4; EHF; PCGF2; NHLH2; TWIST1; TAF9; CNOT6; YWHAB; PRDM1; UBE2I; CCDC59; ARRB1; ARID4A; TEAD1; ZNF180; SOX5; PLAG1; FOXM1; ZSCAN16; NFYB; EGR3; HIPK3; TP63; CREM; DBP; TCF7L2; BRD7; GABPB1; PHIP; ZBTB20; FOSB; ZBTB18; XBP1; CTR9; CALR; AEBP1; TAF10; MECOM; CHD7; ZMIZ1
Down-regulation	251	ERBB2; LOXL2; ABL1; IKBKAP; ZMYM2; HDAC2; DAXX; ITGB3BP; ZFP36L2; GMNN; RBM39; MED15; CITED1; MED16; TCEA1; SOX9; BIRC2; ETV4; TRIP6; TRIM27; TAF6; DNAJC1; MED25; HIRA; SAFB2; GMEB2; LYL1; HOXA10; AIP; ZNF473; TRIB3; XRCC6; BRD8; SCMH1; ZNF76; PSPC1; NR1H2; ZBED2; NPAS2; ATF4; LZTR1; ZBTB17; ZNF131; SOX15; MTA1; HDAC3; C1QBP; RUVBL2; RNF138; ZBTB7A; ZNF410; FOXF1; ZNF593; SUPT5H; MED23; CITED2; ZNF688; TRRAP; NELFB; E2F3; FOXJ3; PBXIP1; ZNF446; PHF1; MYF5; DDIT3; FOXF2; NR2C1; CCNC; CREG1; PHF20; MEF2D; ZBTB40; ZNF211; HHEX; CAMTA2; RXRB; ZNF444; SRCAP; YAP1; TRIP4; PPRC1; NRIP1; ZFX; RBBP8; SETD2; E2F8; MED17; MAF; PMS1; STAT1; ZNF12; IRF3; PTRF; SMARCD3; TBX3; PEG3; TOX; SAP18; ID3; WWTR1; PRPF6; POLR3C; KAT6B; HOXA11; ZNF671; ZKSCAN1; HIVEP2; CIZ1; TLE4; ZNF23; ZNF250; ZNF16; MAFG; BATF3; ZNF189; TOX4; ZNF83; RCOR3; ERCC2; SSBP2; RLF; MKL1; STAT6; USP21; UIMC1; ZNF532; ZNF430; EMX2; ZNF419; TGIF1; MZF1; AES; TRIM28; HIC2; CBX7; CREB5; THAP10; FOXC1; ARID4B; CNOT2; PCGF3; CEBPG; ID2; REXO4; SIX1; NFYA; IRF7; ZNF426; ZKSCAN5; TRAK1; ZNF415; TSC22D3; RUNX1; SUB1; ELF1; NR2F2; ZNF263; SUPT6H; LITAF; RNF10; ZNF324; EYA1; ZNF652; CBFA2T3; SUPT3H; ZNF394; HIPK2; GTF3A; TBL1XR1; MNDA; CALCOCO1; CTCF; SPEN; HES1; ELK3; NPM1; ORC2; SREBF1; ZNF184; TCF4; COPS5; IRF9; RREB1; ZNF350; ZNF91; HMGXB4; ZNF44; NCOR1; FOXK2; SIX2; VEZF1; ZFP36L1; HDAC9; SMARCB1; ZBTB16; SLC2A4RG; ERF; ZNF589; SMARCE1; GATAD2A; ZNF84; CCNE1; SETDB1; SP140L; SCAND1; UBE2L3; LIN28A; TAF1D; RNF6; RING1; JARID2; ZNF107; SHOX2; RFX5; ZNF423; CTBP1; SIRT7; KLF6; ID1; DNMT3B; TDP2; PIAS1; HMGN3; PFDN5; ZNF273; MAX; HOXD1; SALL1; EN1; TEAD4; IRF1; TRIM22; RNF14; BHLHE41; ZHX2; KLF1; KAT2B; CARHSP1; NANOG; ST18; SATB2; TRIM29; MYRF; OSR2; DMTF1; SNAI2; CD3D; RBPMS; POU2AF1; BASP1