Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID72706	Hyoscyamine	GSE92742	SKB	Human	24h	10uM	EID0391

Response Information :

Types	Number	Response transcription factors
Up-regulation	103	NFATC3; DAXX; PCGF2; ZSCAN31; ESR1; MLXIP; SOX12; HDAC7; TBX21; NKX2-2; TERF2; HOXA5; KLF10; CREB1; TEAD3; HOXD13; ZNF177; NR0B1; CNOT6; RBL1; ZNF512B; ARL2BP; EYA2; KLF1; RB1; SIAH2; MYCN; SPDEF; TAL1; ACTL6A; PRRX1; IRF9; NFE2; FOXJ2; ZMYND8; TAF9; CITED2; KLF2; ZFPM2; PIAS1; ZNF189; TCF21; ZNF562; PIAS3; TFDP2; RXRA; ZNF117; MED21; TRIM24; FOXL2; GRHL2; SP2; TULP3; NR2F1; FOXJ3; ZEB1; HOXB2; NAB2; NEUROD1; MEIS2; ARID1A; ZNF239; TFAP2A; NR4A1; IRF6; MEIS1; HOXB7; IFI16; TP63; ZNF140; ZNF394; CD3D; AEBP1; KLF4; ETV5; TRIM22; SALL1; ZNF43; TEAD4; HLF; NR4A2; LEF1; DACH1; SOX17; NR2F2; PEG3; CDK2; TGFB1I1; MAGED1; EHF; STAT1; IRF1; ZSCAN18; FOXM1; WT1; MNAT1; MED1; NFE2L3; ZNF91; MAFB; ID1; TDP2; MYBL1
Down-regulation	140	PUF60; ZMYM2; PSPC1; NR2C1; NAB1; SUZ12; PHF20; RBM39; PLAGL1; CXXC1; ZNF432; ZNF24; ISL1; CREB5; E2F5; SREBF1; FOXG1; TAF1D; AIP; CERS6; ZNF302; MBD2; HSF1; NFIL3; MTDH; CEBPD; TCEA1; ZBED2; XRCC6; KAT6A; PFDN5; PATZ1; NCOA6; CDX1; C1QBP; NR1H3; NR1H2; BRD8; EWSR1; IRF4; SAP18; NFATC4; SIX3; MAF; PBX3; PLAG1; KLF7; BCL10; KDM5B; BBX; PDLIM1; SETD2; PPP1R13L; COPS5; ZNF165; FOXO1; ZBTB38; TRIM29; ADNP2; SAP30; PBRM1; NFATC1; RUVBL2; KAT5; BTAF1; PEX2; VPS72; MED4; TBP; ATF4; NUP62; PRKDC; KLF9; SMARCA5; PSMC3; SCAND1; NCOA2; SMAD7; ZNF721; TFDP1; BTG1; PREB; ARNTL; PMS1; BHLHE40; SMAD2; SMARCE1; TRPS1; HEY1; SOX9; BRD2; NEDD8; KDM5D; TLE4; INSR; ZFHX4; RYBP; FUBP1; ZBTB18; ARID5B; ETV1; FOXD1; NFIB; RBBP7; IRF2; NKX2-1; TLE1; SSBP2; TGIF2; KLF5; CTNNB1; MEF2A; ELF5; MYRF; HDAC9; DDX17; ING3; HMGN3; NFKB1; NKX3-1; JUND; SMARCA4; TFAP2C; BHLHE41; CALR; ATF3; TSC22D2; LMCD1; MITF; SIX2; ADRB2; CHD7; MEOX2; ZIC1; JUP; PBX1; TBL1X; DMTF1; HOXC6; EGR1