Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID72624	Timolol	GSE92742	SKB	Human	24h	10uM	EID0391

Response Information :

Types	Number	Response transcription factors
Up-regulation	111	RELB; NFKBIB; DAXX; ZNF711; PSPC1; ZNF22; SOX11; HMGB1; ZNF250; TCF4; RCOR1; TEAD3; PIAS4; MYT1; PRDM2; SERTAD2; BACH1; NOC2L; NKX2-2; PITX2; SLC2A4RG; NR0B1; ZSCAN32; ZNF281; TCF7L2; JUN; MXI1; PCGF1; CUX2; ZNF623; RORA; GRHL2; CTCF; E4F1; HEY2; ZNF165; ZEB1; CREB3L2; TWIST1; GTF3A; SIX3; SOX5; ZNF117; ZNF3; FOXJ3; ZNF273; IRF6; PSMC3; SOHLH2; PAX6; DLX5; DLX4; MYCN; PIAS1; ZNF589; SAP130; CBFA2T3; ZNF410; ID1; BCL11B; TFDP2; ZNF232; ZNF239; HIC2; NKX2-1; INSR; PBXIP1; TLE4; HOXA11; GABPB1; ILF2; ATF3; HOXA5; MYB; KLF10; HMGB3; SALL1; TCEA2; HTATIP2; ZNF423; CDK8; ZFP36L2; CAMTA1; RXRA; AR; CDK2; IRF7; DLX2; FOXC1; IRF9; CEBPD; CITED2; ZNF43; TAL1; MEF2C; EMX2; AEBP1; NFE2; BCL11A; TGFB1; MAFB; TFAP2A; TEAD4; TDP2; MEF2A; ID4; POU2AF1; MEIS2; CD3D; TRIB3; MYBL1
Down-regulation	118	USP22; SOX15; SFPQ; ZBTB38; TOB1; ZNF302; UBP1; NR2C1; PATZ1; ZNF146; KAT6A; FOXA1; ZNF131; MECP2; HDAC1; EHF; REPIN1; MAF; XBP1; COPS2; ASH2L; ZMYND8; CREBL2; NRIP1; FOXF1; BBX; DNAJC2; HIF1A; MBD2; BIRC2; SIN3B; HMGA2; ZNF160; PPARG; KLF9; BPTF; YAP1; BASP1; TRIM22; PHF8; SMAD4; TOX3; CBX6; NUP62; PIAS2; ZNF580; HOXD1; SREBF1; ADNP2; MITF; SMAD3; ZNF384; C1QBP; ZNF587; ZZZ3; SMARCA2; NCOR1; RBBP7; ZNF652; MED1; TRIP6; RBBP8; POU5F1B; MNT; ATF1; NFIL3; HOXA10; ZNF83; ITGB3BP; IRF8; SAP30; EYA2; ZIC1; ARID4A; PEG3; HEY1; VEZF1; SMARCE1; RBPMS; SPEN; YBX1; BRD2; IFI16; RFX5; HSBP1; DDX17; SMAD2; CRK; RUNX1; TRIM29; BHLHE41; NR2F1; SP140L; HDAC9; FLNA; TBL1X; ETS1; KDM5D; NCOR2; FOSL1; TAF10; PBX1; SOX9; BTG1; INSM1; TCEA1; NR2F2; LMCD1; MEOX2; GATA6; NR1D2; STAT1; CREB3L1; PITX1; TLE1; MEIS1; MSX1; EGR1