Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID72592	Hexylcaine	GSE92742	SKB	Human	24h	10uM	EID0391

Response Information :

Types	Number	Response transcription factors
Up-regulation	155	ACTL6A; JUN; MAFF; YEATS2; PCGF1; ZNF135; TRPS1; MYCN; ZBED2; VPS72; ZNF544; ZNF85; SMARCC2; HDAC9; SRCAP; TCF3; HIVEP1; PRKDC; EED; HOXB2; ZNF74; SALL2; ECD; ATF2; PRDM14; RAD21; OVOL2; SSBP3; IFI16; XRCC6; TCEA2; GLI1; ZNF576; NFKB2; GRHL2; YEATS4; PHF20; HMGB1; BNC1; GLI2; POLR3C; CREB3L2; TWIST1; IRF6; CBX7; PRDM2; ATN1; ESR1; NFE2L3; IRF9; ERBB4; ZSCAN18; TFAP2C; ZNF573; ZNF239; ZNF264; HOXD1; ZNF415; ERG; EZH1; CERS6; CNOT6; VGLL1; ZNF22; MYBL2; ZNF329; CALCOCO1; TULP3; SOX13; NKX2-2; DEK; BCL11A; ZNF43; WT1; AR; ZNF217; ZNF350; ZNF93; CRYM; CREB1; ZNF117; HMGXB4; SSBP2; TGS1; ZFP36L2; ZEB1; SOX9; VDR; EN1; PIAS4; ZNF32; CERS4; NEUROD1; ST18; RYBP; CUX2; MEOX1; ZNF589; REL; NFE2; E2F8; TTF2; RERE; NR1H2; THAP10; NFIB; NR0B1; CNOT2; ELK3; CBFA2T2; ZNF331; TDP2; NCOA2; ZNF140; FOXM1; PEG3; MYBL1; PRDM1; KLF10; LITAF; TERF1; ZNF91; TAL1; KLF11; ZBTB16; SOX17; HHEX; GMNN; SMAD7; DLX5; TOX; ZNF423; TAF11; MYRF; NANOG; INSM1; KAT2B; EHF; MKL2; ARID1A; HES1; ZNF274; CDK2; DNMT1; RORA; TFAP2A; ZMIZ1; TRIB3; MYB; ID4; BHLHE41; CALR; PBX1; DMTF1; MAFB
Down-regulation	144	ATF5; PUF60; KMT5A; NCOA6; FOXD1; PRPF6; YBX1; NFKBIA; ENO1; SMARCA5; HDAC1; FLNA; TRIM28; PSPC1; HMGN3; TFDP1; CDK9; ZNF189; ERBB2; MYOD1; ZEB2; AATF; BTG1; TCERG1; TP53; DNAJC1; FOXG1; CRK; CARM1; MTDH; FOXJ3; MBD2; USF2; PSMD9; KLF6; HSF2; RBBP4; PTTG1; NELFB; HNRNPD; ASH2L; CIZ1; NPM1; ZNF281; NCOA4; MNAT1; MYF6; COPS2; PITX2; MAX; FHL2; EDF1; HMGB3; CXXC1; PREB; MXD4; SP140L; MAGED1; ZNF672; ALX1; CDK8; EMX2; SIAH2; PIAS2; ING2; NR2F2; ID2; ZFHX4; ZZZ3; USP16; SAP18; BRPF1; THRAP3; RLF; PCGF2; MED1; NFE2L1; TRIP6; ATF4; ID3; SAP30; GABPA; ENY2; NFKB1; ZBTB18; ZHX3; SIX1; HSBP1; BRD2; ASXL1; CITED2; TAF10; TSC22D1; CCDC59; MTA1; PPARGC1A; ADNP2; TBL1X; RBBP7; UBE2I; NCOR2; TCF12; HOXC6; HEY1; NONO; FOXO4; STAT1; MEF2C; NUP62; RAN; SATB2; NRBF2; NR1H3; HOXB7; KDM5D; KLF2; MYCBP; ELF1; RNF14; TRAK1; ARID4B; BASP1; BATF; FOSL2; PTRF; PURA; SMAD3; NFE2L2; CREB3L1; CEBPD; HMGB2; FOSB; WWTR1; RUNX1; MSX1; CTNNB1; MAF; TOX3; OSR2; GATA6; CHD7; HIPK3; ID1; TSC22D3