Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID72577	Metolazone	GSE92742	SKB	Human	24h	10uM	EID0391

Response Information :

Types	Number	Response transcription factors
Up-regulation	60	PCGF2; NKX2-2; OLIG2; TCF4; ZNF195; SOX11; ZNF202; ZNF225; HEY2; PRDM10; ZNF675; SKIL; ZFP69B; EGR1; ZNF85; POU2AF1; ZNF415; ZNF682; E2F8; TCF12; SALL2; SALL1; NR1H4; RB1; ZNF273; TWIST1; NR0B1; CAMTA1; ZIC1; MED1; NLK; GABPB1; KMT2A; PROX1; FOXJ3; NFE2; ETV5; SAP30; MNDA; ZNF239; ZEB2; KAT6B; RXRA; EMX2; TFDP2; BCL6; MTA1; TAL1; MEOX1; MED13; CRYM; ZNF117; ZNF423; EGR2; MAFB; ZNF91; MECOM; BASP1; HOXC6; MYBL1
Down-regulation	91	USP22; C1QBP; FOXF1; UBP1; CITED2; NR2C1; ATF1; BIRC2; HDAC1; MXD4; EP300; ENO1; SAFB2; ZBTB38; TRRAP; ZMYND8; MDM2; STAT6; RUNX3; ALX1; TOB1; SFPQ; CITED1; ZKSCAN1; CHD1; RELB; ISL1; NR2F2; SP140L; ZNF783; LIMD1; CTBP2; RNF6; HOXA1; IL16; SERTAD2; PLAGL1; PRRX2; ZNF264; TRIM28; KLF6; FLNA; CRY1; ZNF146; EHF; MED23; ARNTL; HOXA11; TCF21; CTNNB1; MEF2A; NUP62; INSM1; SMARCA4; NFKB1; RNF4; TRIP6; YWHAB; MAF; HOXD1; FOSL1; CBX3; RBPMS; ZBTB20; STAT5A; PIR; EYA2; SPEN; BTG1; HMGB2; RFX5; FOXC1; RNF14; ID2; ZBTB18; SREBF2; SNAI2; CTR9; GATA6; KDM5D; PTRF; TBL1X; SSBP2; ZNF217; WWTR1; FOSB; TLE1; MEOX2; MITF; TAF10; BCL11A