Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID72520	Brinzolamide	GSE92742	SKB	Human	24h	10uM	EID0390

Response Information :

Types	Number	Response transcription factors
Up-regulation	173	SIX6; SUPT3H; NR5A2; RRN3; ZHX2; TAF11; SKIL; TAL1; TDP2; ZBTB20; HEY2; SALL1; AR; POU4F2; ZBTB3; THAP1; NCOA2; ERBB4; ZNF239; ZNF329; TERF1; HLF; ZNF571; NANOG; ZNF492; CRYM; THAP10; ZFP69B; HHEX; SALL2; HOXD1; WT1; PBX1; PRDM10; KLF1; COPS5; SUMO1; TAF5; MED14; IFI16; ZNF562; ZIC3; YEATS4; LIN28A; CAMTA1; CREM; ZNF85; HDAC9; ELK4; ST18; ZKSCAN8; GFI1B; ZNF254; KAT2B; ZNF682; POU2AF1; CDC5L; BCOR; NEUROD1; ZNF268; ZNF544; GMNN; LITAF; HIVEP1; TOB1; HMGXB4; BACH2; PKNOX2; TULP3; ZNF217; SPIB; ZFPM2; ZNF136; ZBED2; ZNF224; ECD; MYBL1; NFE2; MEIS2; ZNF43; TBX21; CD3D; PTTG1; ZNF12; ZBTB44; TTF2; ZNF589; ZNF423; ZNF74; TCF7; NR0B1; MKL2; CITED1; TRIM24; HOXA11; ZNF529; GATA1; SAP18; SOX17; PIAS4; ZNF140; MED13; NR1H4; EN1; CUX2; ZMIZ1; SOX2; ZNF354A; TCF21; RBFOX2; TGIF1; C1D; ZNF350; BARX1; ZNF10; ZNF345; CERS4; ZNF331; SSX1; TLE2; SOX13; DEK; BNC2; CDK2; TFAM; FOXF2; ZFP36L1; REL; MEOX2; ZNF611; IRF2; ZNF721; ZNF652; RREB1; PEG3; IRF9; SPDEF; TBX3; TOPORS; TGFB1I1; RAD21; ZNF117; CREB3L2; CEBPD; KAT7; ESR1; NKX3-1; TOX; STAT4; LEF1; RBPMS; TFAP2A; SNAI2; KAT6B; TEAD1; IRF6; ZNF91; NKX2-2; PAX5; TFDP2; HOXB2; FOXO1; BIRC2; DACH1; NKX2-1; TRIB3; ZNF232; TCEA2; TLE1; ID4; SOX11; BCL11A; MYB
Down-regulation	222	ATF5; VGLL4; FLNA; MNAT1; CXXC1; RUNX1; ENO1; USF2; TRAK1; NCOR2; MAFG; YBX1; NELFB; BRD3; FOXC1; UBE2I; DNAJC1; CIZ1; ZNF629; KLF6; KLF4; ZNF672; CRK; ERF; ELK1; PUF60; CASZ1; NFKBIA; ZIC1; ZFHX4; RBBP4; CENPB; BATF; TRIM28; KDM2A; ZHX3; SCMH1; TCF12; TAF10; SMARCE1; EDF1; HR; NFE2L1; NRIP1; KLF3; PKNOX1; RHOA; CHD4; ATF7IP; ZNF282; NR2F2; MXD4; MBD2; ATF6; ZNF768; ASH2L; MED27; PML; FOXD1; KDM4A; DDX54; YWHAB; YY1; TFDP1; REXO4; MED6; MYOD1; TRIM16; FOXJ3; PAXBP1; YAF2; BRPF1; MAP3K10; RBM39; KMT2A; MEF2A; TFCP2; ZBTB1; HSBP1; TBL1XR1; PURA; TRIM29; FOXO4; EHMT1; EPAS1; MBD1; DMTF1; ERCC2; APEX1; PPARGC1A; ESRRA; AIP; PRRX2; HDAC1; SIX1; MAX; NFATC1; PSMD9; CDK9; ZBED1; HMGA1; GFI1; NRBF2; RUVBL2; IRX5; IRF5; GATA4; RELB; MAGED1; ELF1; DEAF1; ZNF446; NCOA4; BRD4; ID2; KMT5A; TBP; MYRF; BHLHE41; SOX9; ATF4; HEY1; NR1H3; ZNF384; ZEB2; SMARCA5; REPIN1; MEF2C; SPEN; SIRT7; RCOR1; HOXC6; GTF3A; ZNF189; SMARCD2; RNF14; DDX5; BCLAF1; ARNTL; TSC22D4; BTG1; SFMBT1; TADA3; NFKB1; SIAH2; AATF; RNF141; ARNTL2; SAP30; VEZF1; KLF7; GTF2I; NFE2L2; MMS19; RUNX3; PATZ1; UBE2L3; WNT4; KMT2B; HMG20A; NCOA1; STAT2; MED15; GABPB1; SERTAD2; LIMD1; FOXN3; PSPC1; JUNB; IL16; CBX6; ZNF281; ID3; BMI1; RBPJ; ARID4A; ZBTB40; HIPK3; CUX1; TAF12; THRAP3; SETD2; ZZZ3; CARHSP1; TSC22D2; TGFB1; CITED2; SOX4; USP22; ZKSCAN1; ZFP36L2; ASXL1; MED1; ASCL1; FUBP1; NUP62; HMGN3; BRD8; HIVEP2; NFIB; AEBP1; PCGF2; TAF1D; CTBP2; BAZ1A; HMGB3; SMARCD3; IRF7; HTATIP2; DNMT1; FOSB; SMAD7; ERG; PAX6; ID1; MAFB; TCF4; XBP1; TRIP6; ELK3; KLF2; KDM5D