Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID72501	Loperamide	GSE92742	SKB	Human	24h	10uM	EID0390

Response Information :

Types	Number	Response transcription factors
Up-regulation	107	COPS5; TERF1; TDP2; HMGA1; EP300; PCGF1; MYBL1; NOC2L; HMGXB4; ZNF667; NEUROD1; MNDA; ST18; NCOA2; EWSR1; EHMT2; C1QBP; PRKDC; ZNF573; PEX14; TCEA1; ZSCAN16; ZNF224; NR1H2; TAF9; ZIC3; TEAD3; HIPK1; CDK2; ZNF589; ZNF586; GFI1B; ZNF268; DBP; TRPS1; TULP3; OSR2; ATF3; SREBF2; CERS6; LITAF; NFE2L3; MED14; SIN3B; HIRA; HOXB13; FOXI1; KLF1; NCOA1; PIAS4; PIAS1; TCF21; ZNF205; POU5F1B; FOXJ1; BRD4; CREBL2; GMNN; TAL1; TFAP2A; AR; ZNF232; ZMIZ1; INSM1; KLF4; SOX13; ZSCAN18; LIN28A; KLF11; IRF8; ESR1; TCF7L2; DNMT1; INSR; MYCN; E2F8; CD3D; THAP7; SIX3; ERBB4; CERS4; ARNT2; SOHLH2; CHD7; TOPORS; THRAP3; HOXB2; ZNF350; ID4; RAD21; ZNF652; KAT6B; NANOG; ATN1; SAP30; BCL11A; EHF; VPS72; SUB1; TBX3; AHR; TOX3; NR2F1; SOX9; TRIB3; SNAI2; IRF6
Down-regulation	135	HMGB1; SMARCE1; BRD3; WWTR1; KDM2A; LOXL2; GABPA; NELFB; YBX1; GTF3A; ZBTB38; NONO; GTF2IRD1; SNIP1; HSBP1; FOXO3; BAZ1B; TRIM16; PLAGL1; PIAS2; TLE4; NCOA4; MYCBP; MED21; STAT5A; NEDD8; RHOA; RUVBL2; TBP; SIX1; USF2; APEX1; PREB; KDM5A; AIP; ZNF226; NFKBIA; TAF10; NFYC; SPEN; SMARCA5; NFKB1; MAGED1; HMGN3; ARNTL; RCOR1; PPP1R13L; ARID4A; TFCP2L1; SATB2; ELF4; TRIM28; EDF1; TCF25; ZNF528; ORC2; SUV39H1; RYBP; PAX8; AATF; RLF; GABPB1; BASP1; GTF2I; BLM; TCFL5; RORA; MEIS1; NFIB; TCF12; ARNTL2; TLE1; MBD2; ZNF410; ZNF22; SFPQ; NRIP1; TRIM32; RNF141; RBM14; HIPK3; TRIM29; RAN; FOXA2; CBFB; PSPC1; ZMYM2; NFATC1; MTA1; CHD3; PLAGL2; MED1; MED6; PAWR; ELF1; FOXG1; ZMIZ2; ERG; CBX3; FOSL2; RBL2; CRK; SMAD3; IRF4; BMI1; ID3; PFDN5; SERTAD2; SETD2; CEBPD; MYC; NUP62; BRD2; MECOM; PHF20; KLF5; HLTF; EZH2; TCF4; SMARCA1; EGR3; NKX2-1; TRIP6; ETS2; RFX5; JUP; ELK3; HOXD1; SMARCD2; SOX11; IKZF1; MSX1; HMGA2; PBX3; HOXC6