Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID72345	Metolazone	GSE92742	SKB	Human	24h	10uM	EID0390

Response Information :

Types	Number	Response transcription factors
Up-regulation	101	SSBP2; TULP3; ZNF562; SALL2; PRDM10; NR5A2; POU2AF1; SUMO1; PAXBP1; LITAF; TGS1; ZNF224; ZNF12; ZNF268; TAL1; SPIB; SALL1; HEY2; ABL1; ZBTB20; ZBTB44; TDP2; ZNF136; ZNF43; HMGXB4; ZNF195; ZNF239; ATF3; CREB3L2; AR; FOXF2; ZNF331; TCF3; IRF9; ZNF544; HOXB5; DLX5; MNDA; CDK2; KAT2B; THAP10; GMNN; TBX3; CERS4; HMGA1; E4F1; ZNF500; NFE2; SOX2; ZNF589; BNC2; MEIS2; DNMT1; GFI1B; SPDEF; ZIC1; PBX1; CD3D; ARID5B; ST18; FOXF1; KLF1; ZNF117; SSX1; MYBL2; SOX13; CHD8; TRIB3; TCF21; FOXE1; HOXA11; FOXM1; ZNF611; CREB5; ELF3; PRDM14; IFI16; PHIP; NANOG; PAX5; ERBB4; KAT6B; ARNT2; MYBL1; VPS72; HOXB2; IRF6; ATN1; MXI1; SHOX2; CUX2; ZMYND8; NR0B1; ZNF423; ESR1; SMARCA1; SOX11; TCEA2; BCL11A; TFAP2A; HMG20B
Down-regulation	160	FLNA; KLF4; BRD3; SMARCE1; NCOR2; FOXN3; CEBPA; ZNF672; UBTF; DR1; ERF; KDM5B; EPAS1; ENO1; ASH2L; USF2; AATF; ATF7IP; TRAK1; CRK; KDM2A; SIX1; TRIM28; MNAT1; RUNX3; RNF138; SMAD4; SNW1; MYC; MBD2; VEZF1; RBL2; TGFB1; TRIM29; SMARCA5; ZNF7; ARID4A; NFATC1; ZMYND11; AHR; PSIP1; MAF; CREB3L1; TOB1; ZBTB38; BATF; SFPQ; RBBP4; MNT; TXNIP; HNRNPD; RBM14; PPARGC1A; NR1D2; RARA; NRIP1; IRX5; YBX1; SPEN; NCOR1; STAT5B; MEF2A; BCL11B; BRPF1; FOSL1; BAZ1A; MXD4; NCOA6; KLF9; NFE2L1; NR2F2; TAF9B; SMARCA4; FOXC1; BMI1; NCOA4; BLM; SP3; TOX3; MAGED1; SMAD2; CHD1; STAT3; SMARCA2; NUP62; CBFB; TRRAP; XBP1; POLR2A; RELA; PHF20; CTNNB1; TAF10; YWHAB; EGR3; ELF1; MED6; JAK2; HIPK3; ING2; NFAT5; ZBED1; PURA; TRIM16; BCLAF1; TLE1; SETD2; IKBKAP; HMG20A; INSM1; SERTAD2; ZNF131; HMGN3; ZMIZ1; NFIB; NFKB1; ZEB2; PPARG; ZMIZ2; ATF1; REST; HOXC6; LPIN2; EHF; USP22; SIAH2; CRY1; SOX9; TSC22D2; GTF2I; PCGF2; ZNF267; TMF1; NCOA1; HLF; UBE2B; SMAD5; FOXD1; ZBTB18; MEF2C; MTDH; SMARCD2; LEF1; SNAI2; HMGA2; SMAD7; MAFB; SMARCD3; KLF5; ELK3; HOXA5; ASCL1; CITED2; ZMYM2; BIRC2; KDM5D; KLF2; HOXD1; TRIM22; IKZF1