Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID72342	Orphenadrine	GSE92742	SKB	Human	24h	10uM	EID0390

Response Information :

Types	Number	Response transcription factors
Up-regulation	104	ZNF12; LITAF; ZNF394; KAT2B; TGS1; ZNF329; SCAI; POU2AF1; CBX7; PLAGL1; TCF7; SSX1; GTF2IRD1; ITGB3BP; BPTF; SALL1; ZHX2; ADNP2; CCDC59; THRA; ZBED2; HIF1A; SOX15; ZNF274; MNDA; LEF1; MECP2; CREBL2; ZNF239; SOX10; HMGXB4; GMNN; RNF138; CBX5; TP63; HBP1; C1QBP; DNMT1; HMGB2; ZNF529; TCEA1; CNOT2; ZNF136; IRF2; ZNF304; CREB3L2; PHF1; NR3C2; HOXA10; ZNF331; MED13; CBFA2T2; TOX; ATF2; YEATS4; TRRAP; IFI16; RREB1; ING3; MAFF; FOXF1; TFAP2C; TOPORS; RBPMS; ZNF148; CD3D; FOXE1; ST18; CITED1; ABL1; CREB5; MED24; RBBP8; BCL10; SMAD7; ZMIZ1; TBX3; PSIP1; USP22; NR0B1; ZSCAN18; ATF1; TRIP6; ATF3; PITX1; PAX5; IKBKAP; MEIS2; NANOG; NKX3-1; MAGED1; TGFB1I1; TGIF1; AHR; TLE1; HMGA2; BHLHE41; RFX5; BBX; TRIM22; KLF2; BCL11A; TRIB3; KDM5D
Down-regulation	96	FLNA; EPAS1; NELFB; ERF; AATF; PROX1; DACH1; PREB; STAT5B; PRPF6; SNAI1; ENO1; CXXC1; FOXC1; IRX5; EDF1; TFDP1; PRRX2; RUNX1; MEF2A; TCEB2; KLF6; TP53; ZNF281; SLC2A4RG; NAB1; LMCD1; MAF; MYCN; UBTF; UBE2L3; PTRF; ESRRG; FOXN3; TGFB1; STAT3; CENPB; GFI1; MAZ; BRD7; RARA; GATA6; ZBED1; EMX2; BLM; TRIM28; HLX; TAF9B; KLF7; SIM2; GTF3A; ESR1; MYCL; HOXC6; SMARCB1; PA2G4; SOX4; INSR; SIX1; KLF9; TOX3; VDR; DMTF1; CARHSP1; NR2F1; YWHAB; ID1; TSC22D2; SPI1; TXNIP; MEF2C; DLX2; BMI1; AEBP1; ELF1; HOXB6; HIPK3; MECOM; TAF1D; CEBPD; HOXB7; NFIB; PSMC3; ETS2; SPEN; CITED2; SMARCD2; HMGB3; ERG; ASCL1; PAWR; SOX9; NUP62; MYB; ID4; IKZF1