Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID72293	Fasudil	GSE92742	PHH	Human	24h	10uM	EID0389

Response Information :

Types	Number	Response transcription factors
Up-regulation	173	ZFP36L2; ZNF43; WDR77; IRF6; ZNF91; BARX1; NFATC4; FOXF2; ZEB1; ZNF133; ZNF117; AEBP1; OLIG2; HOXB5; VPS72; TWIST1; HOXB6; HDGF; HOXD3; HOXA3; HOXB2; RING1; DLX2; NKX3-2; LHX3; SIRT2; ZSCAN18; TRIM29; ZNF75D; EZH1; NHLH1; NPAT; TGFB1I1; MYBL1; HOXB1; MED14; TLX1; GATA1; CDIP1; LHX2; TAL1; DLX4; TP73; SPDEF; SOX17; CHD3; ZNF239; ZKSCAN8; ZNF232; KDM5C; NOC2L; KMT2D; ATF3; ZNF85; RBM39; FOXJ2; TRIP11; KLF13; RELA; PAWR; FOXM1; ZNF195; VGLL1; PIAS4; HINFP; MYCL; THRA; ZNF510; CDX1; DEK; E4F1; CXXC1; ZNF93; NKX2-2; RFXANK; ING4; BTF3; DNMT1; JUP; PBX3; HOXB9; MXI1; MECOM; HSF4; BRD3; PRDM10; SOX10; DLX5; CCNH; NFX1; PHF1; SSBP3; TCFL5; TCF7L1; GATA6; BNC1; KLF7; TCF12; LITAF; BCL11A; ZNF257; TRIM25; TCF7L2; TULP3; CBFB; MDM4; OVOL2; LYL1; BLM; CALR; ZNF165; PDLIM1; SUV39H1; MEIS1; FOXJ1; ZNF141; EN1; FOXG1; DBP; HOXA6; NFE2; CAMTA1; NEUROD1; ZNF177; MYBL2; PRDM1; PAXBP1; CREB3L2; IRF9; NAB1; HIVEP2; SHOX2; ERBB4; DDIT3; PHIP; BACH2; JUNB; KLF11; TXNIP; YAP1; CHD7; TFAP2A; ZNF107; RBL2; DDX17; TTF2; MYB; RXRA; UBE2L3; FOXD1; INSR; STAT4; ELF3; TRPS1; ID4; TGIF2; SOX2; ARID5B; PMS1; OSR2; PAX6; FOXA2; FOS; ZNF331; HOXA5; ZNF589; TOB1; FOXN3; ESR1; NFE2L2; NR4A2; ID3; WT1
Down-regulation	195	USP22; CCNA2; MTF2; CRK; NRIP1; ING2; EZH2; IKBKAP; GABPB1; ENY2; SFPQ; NRBF2; NANOG; ZBTB38; SAP30; MTDH; MYCBP; NCOA4; CREBL2; AHR; MED4; TFEC; CTR9; TSG101; BTG1; HLTF; ZNF12; FOXJ3; NEDD8; TBL1XR1; ZNF302; IRF8; TERF1; BHLHE41; ATF5; NR2F2; XBP1; PEX2; RBPMS; TSC22D1; NFYB; ZNF146; WWP1; EGR2; RNF6; SMARCA5; BRD8; ZNF267; ZNF23; ZEB2; RNF10; SP140; MITF; UBP1; ASH2L; PCBD1; FOXA1; MED6; HLF; STAT6; HEY1; PHF8; NR0B1; USF2; TRIP6; SAFB2; NKX3-1; WWC1; MED23; ZZZ3; SMAD3; TRIM28; TGS1; PAX5; C1D; EDF1; PIAS2; TOX3; DR1; ZNF148; MBD2; REPIN1; MED24; TRIM22; CEBPD; LZTS1; PLAGL1; ARNTL; CHD1; SREBF1; MAF; ZNF226; HSF2; TCEA1; ZNF134; KDM5D; MED7; ADNP; SSX1; IRF2; ZBTB1; PTTG1; RBBP4; NFE2L1; RBM14; HBP1; ERBB2; ATF7IP; SMARCA4; SIX1; MAFB; COPS5; MSC; POLR2A; JARID2; WWTR1; HIC2; ZNF189; ITGB3BP; RAN; BCL3; KAT6B; NR2F1; HMBOX1; ZNF432; TLE4; MAGED1; ATF1; TGIF1; ZNF536; ARID4B; SP3; PTRF; DNAJC2; FOSL2; HTATIP2; TBL1X; DNAJC1; RNF14; ERG; KAT7; NCOR1; SIAH2; ARID4A; BMI1; TCEB2; INSM1; TCF4; FHL2; REST; RBBP5; PRKDC; NCOR2; NR1H3; NR3C1; ING3; ISL1; CHD4; CITED1; MEF2C; EGR3; NR1D2; FLNA; PCGF2; ZNF532; BBX; CRYM; ZBTB11; NFAT5; ZMIZ1; IRF4; SOX9; EYA1; PIR; BASP1; ZMYM2; TBX3; TOX; MAX; ZNF84; ZBTB16; SPEN; NPM1; MNDA; ELK3; HDAC6; GATA2; TGFB1; CREG1; ZBTB18; BATF; POU4F1; KLF2; CEBPZ; TLE1