Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID72256	Febuxostat	GSE92742	PHH	Human	24h	10uM	EID0389

Response Information :

Types	Number	Response transcription factors
Up-regulation	70	IRX5; SOX4; HOXD10; STAT3; FOXF2; MLX; FOXG1; PIAS1; DNMT1; TRIM33; EZH1; TAF1D; PIAS3; NPAS2; TFEC; LEF1; SPIB; TULP3; ELF3; ELF4; RNF141; JUP; HOXA11; SIM2; TOX; ZNF586; CUX1; MED23; TOB1; ZNF217; CTBP2; TRIM16; MLXIP; ZNF83; LOXL2; MEF2A; TGFB1I1; OLIG2; MECP2; AEBP1; SMAD7; RFX5; ZBTB18; TFEB; MYB; EYA2; PGR; PURA; PRRX1; ID3; ING3; CREB3L2; TLE4; HOXC6; MYRF; NKX2-1; EN1; NKX3-1; SMARCB1; TBX2; SP140L; PSPC1; ID1; POU2AF1; PBX3; FOSL2; TRPS1; APEX1; NR1H2; PITX1
Down-regulation	70	NFIB; ZNF43; ZNF329; SUB1; SMAD2; ACTL6A; SP3; JUND; NAB1; ZBTB38; KLF7; GFI1B; CTBP1; ATF2; SMARCA1; ZNF146; PAX8; ZEB1; CRY1; PPARGC1A; TOX3; PLAGL1; EHF; NR2F1; PBXIP1; SHOX2; PIR; ATF1; CENPF; ZIC1; IFI16; ZNF165; BATF3; ZNF143; HLTF; INSM1; TP63; HIVEP1; RHOA; JUNB; ETS1; SMARCA4; GATAD2A; KDM5D; HDAC2; TFDP2; HLX; KLF6; TBL1XR1; DAXX; MSX1; NFE2; SOX11; ZNF652; SMAD3; JARID2; FOXN3; MEOX2; CREM; HDAC9; ID4; CEBPZ; ELK3; ASCL1; TGFB1; CITED1; ZFP36L1; DNMT3B; PBX1; TXNIP