Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID72149	Isorotenone	GSE92742	PHH	Human	24h	10uM	EID0389

Response Information :

Types	Number	Response transcription factors
Up-regulation	219	BRWD1; ZNF43; FOXF2; HMGA2; RELB; OLIG2; FOXD1; ZFP30; ATOH1; ZNF573; AFF4; ZNF165; ELF4; FOXI1; GATA6; SMARCD3; TOX4; PPP1R13L; ERF; TCF21; ZNF10; ZNF701; PRDM10; VENTX; ZNF93; RNF138; VGLL1; RARG; PAWR; ZNF331; MAPK8IP1; ZKSCAN8; BARX1; ZNF180; CREG1; ZNF239; BTF3; MED14; SOHLH2; GABPB1; ZNF85; CDK7; ZNF426; CDX1; EMX1; TP73; ZNF410; MYBL1; TAF5L; ZNF354A; GLI2; RLF; ZNF350; INSM1; SNAI1; ZFP69B; PHF1; SPI1; ZNF236; ZNF345; ELK4; SPDEF; PRDM12; CNOT6; HMGB2; HIPK1; ZBTB6; HOXD3; PLAG1; CBX2; ADNP2; MYCN; RBBP8; SCRT1; ZNF492; ZNF257; KDM5C; DLX2; NFIX; ASH1L; SCAI; ZNF682; MDM4; PKNOX2; JUP; TAL1; GFI1; ERBB4; TGFB1; FHL2; SOX17; SMAD7; ZNF667; TGIF1; NHLH2; HOXA4; NFAT5; DDX17; ZBTB43; TEAD4; ZNF224; EGR4; ASCL1; ZNF215; SMAD4; GRHL2; MYT1L; PITX2; RUNX3; ZNF211; TEAD3; BCL3; HSF1; SOX11; ZNF195; ZNF675; HSF2; GTF2I; NFATC4; ZNF292; EN1; NKX3-2; TWIST1; ZSCAN18; RAD21; NPM1; FOXM1; RFXANK; MAML1; EYA1; TBPL1; ZBTB44; MDM2; OVOL2; BNC1; TRIM29; HOXA6; ZFP36L2; MEIS2; ZMYND11; EGR1; IFNB1; TBX2; FOXO4; HOXA5; NR4A3; RSF1; PTTG1; PAXBP1; HOXA1; BRIP1; CNOT3; MECOM; TAF7; SIX3; ZNF83; MED17; RCOR1; ID4; WT1; KLF1; SMAD5; FOXL2; TRIM25; FOS; SMARCB1; IRF9; HIC2; TFAP2A; IRF1; ARRB1; BACH1; GATA2; FOXE1; NEUROD1; E2F2; TCEB2; TMF1; FUBP1; HIRA; SKI; ZNF586; GATA3; SMAD6; PURA; ZNF217; TEAD1; STAT4; ID3; ARID5B; NKX2-2; NFE2; NANOG; TOX; ZNF175; DAXX; PGR; ZEB2; PHIP; FOXF1; PRRX1; TCEA2; HMGA1; MYB; ZNF432; PNRC1; NFE2L2; BATF; CHD7; LMCD1; POU2AF1; EPAS1; NR4A2; ZFPM2; CREB3L2; BASP1; POU4F1; PBX3; NFATC3
Down-regulation	218	USP22; CRK; NR2F6; MYC; PARP1; HDAC1; NEDD8; IKBKAP; MYCBP; NFKBIA; HNRNPD; NRIP1; SMARCD2; SREBF1; MITF; ETV5; C1QBP; BHLHE41; KDM5D; ATF4; STAT6; PCBD1; HLF; MMS19; TOX3; REPIN1; PIR; NRBF2; ENO1; RBPMS; FOXJ3; ZMYND8; TRIM16; NELFB; VGLL4; CNOT1; NFIB; RERE; SFPQ; MLX; MAZ; BRD2; ESRRA; TCF12; PPARGC1A; TOB1; BTG1; SOX9; MLXIPL; SIX1; TTF1; RAN; JUN; KAT8; PRPF6; GON4L; ZNF148; ITGB3BP; TBL1X; RREB1; MAF; HMGN3; PREB; HCFC2; PMF1; NFE2L1; MAGED1; SND1; HMG20B; PHF20; ARNTL; ATF6; ZBTB16; TFAM; REXO4; HOXD10; USF2; ZNF189; MYBBP1A; EDF1; TRIM27; CERS6; HOXB7; MED6; ZBED1; TLE1; PBRM1; ATF5; CCNC; ZNF12; TSC22D1; MED4; ATF1; BAZ1B; EED; AFF1; ZNF263; NCOR2; ZNF512B; ZZZ3; PPRC1; ZEB1; CEBPA; WWTR1; HMGB3; URI1; MED24; XRCC6; HTATIP2; HMGB1; ZNF7; TBL1XR1; BIRC2; ZNF652; RNF6; HLTF; NR0B1; MNAT1; PIAS3; KLF6; PTRF; TP53; NCOA6; MXD4; PBXIP1; HDAC9; UBP1; MNT; ZFP64; ZBTB18; PAX8; ZKSCAN1; CEBPZ; STAT5A; CLOCK; ERBB2; RBPJ; AES; PPARG; PATZ1; FOXN3; RORA; FLNA; TSC22D2; KDM2A; MEF2C; ZBTB38; TRIM32; ABL1; CCNA2; AR; MXI1; TCF7; TBX3; ZNF394; CREB5; RBBP4; CENPB; NFYC; E2F6; PRMT2; NLK; SNAI2; NR5A2; CRYM; LPIN2; YBX1; SSBP2; MZF1; SLC2A4RG; TRIM28; CTBP2; BCL6; BAZ2B; LEF1; PRKDC; CHD9; RBM14; JARID2; ING1; RNF14; MEOX1; ZMIZ2; SP110; KLF4; GTF3A; IRF7; TRIP6; SSX1; DDX5; MSX1; HOXB6; ZMYM2; HDAC4; HDAC6; CBX7; ZNF226; BBX; SMARCA4; HOXB13; RNF4; IL16; CBX6; CBX3; XBP1; SIX2; SAFB2; SPEN; NKX3-1; SMAD3; SMAD1; ELF3; EYA2; COPS5; EMX2; SATB1; YWHAB; NR1H2