Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID72041	Loperamide	GSE92742	PHH	Human	24h	10uM	EID0388

Response Information :

Types	Number	Response transcription factors
Up-regulation	148	NR2C2; FOXO4; ZNF254; TDRD3; ZNF571; TSC22D1; PIAS2; CREBZF; CEBPA; TRIM16; MED6; LZTS1; HCFC2; ZBTB3; PIAS1; KAT7; NKX3-1; PAX8; NEDD8; REPIN1; APEX1; FOXD1; RBBP4; SMARCE1; DPF2; MED1; RBM14; DR1; SKIL; RNF10; MSL3; NRBF2; PARP1; RFX7; TTF1; GCM1; ZNF226; RNF4; SIX2; SIX1; LIMD1; ZNF675; RFX5; MED23; MED4; NFKBIA; ZNF189; HSF2; GABPB1; RELA; ZNF302; YBX1; NONO; RBBP7; EED; MED24; TBP; USP22; ZNF184; ZNF468; KMT2B; TADA3; MED12; FOXG1; RAN; RBPJ; LPIN2; MEN1; SNW1; UBE3A; BBX; NR1D2; PNRC1; TFEC; RELB; TSC22D3; CCNA2; UBE2I; NPM1; SKI; PHF8; SNIP1; CREB3L1; ZNF267; CARHSP1; ZNF222; ERG; MAZ; SALL1; ZNF410; SOX18; INSM1; NFYC; CRY1; ZNF165; HIRA; NUP62; MAGED1; HMBOX1; RFC1; MAFB; ARNTL; PIR; ZNF146; TBPL1; ZNF304; ID2; FOXA1; BLZF1; FOXJ3; TBL1X; HOXB7; SMARCA5; ELF5; CREG1; TFDP2; NANOG; EZH2; KAT6B; TRIM28; RUNX3; SLC2A4RG; HTATIP2; TSC22D2; TLE1; DRAP1; SMARCA1; CTR9; NKX2-2; NCOR2; PCBD1; NR0B1; MYCBP; CRK; ETS2; HLF; MTDH; IRF8; MAF; IKBKAP; ZNF652; SPEN; TGFB1; RBPMS; AHR; TRIP6; KDM5D; BHLHE41
Down-regulation	168	SPDEF; NRIP1; ZNF215; HOXB2; BNC2; ZNF133; BACH2; NHLH1; NFIC; PAXBP1; LOXL2; CHD9; MYRF; UBE2L3; LZTR1; ASXL1; CAMTA2; TERF2; MEIS1; ZEB1; CDX1; ZBTB16; PBX3; ESR1; ZNF337; TAF5L; PCGF3; ZNF562; CSDC2; HES1; NCOA1; ZNF444; LHX3; ZNF239; MEIS2; NR4A2; ZNF266; FUBP1; GATA1; MKL2; IRF3; RBFOX2; KDM4C; RBM39; SMARCD2; IRF9; FOXL2; DLX2; RBBP8; PMS1; RING1; ZSCAN18; AR; TFAP2C; ID4; PREB; SOX2; LMCD1; ZNF587; ZNF232; TLE4; ZKSCAN1; BLM; HOXB6; PLAGL2; CCNE1; RUNX1; CHD7; KLF9; CDC5L; STAT6; AFF1; PAX6; IRF4; INSR; SIX3; HOXC4; ZMIZ1; MED25; ERBB4; GATA6; SMARCD3; FOXJ1; KLF13; CBFA2T2; SRF; FOXF2; SSBP3; PHIP; ZNF432; MED17; DLX5; ING3; NFATC4; SERTAD2; RBL2; HHEX; HOXB5; SATB2; ELF3; KLF7; DMTF1; HIC2; ID1; TULP3; SHOX2; FOXF1; FLI1; ZNF331; NFE2; MYBL2; ZNF394; TULP4; BRD4; YAP1; E2F5; CTBP2; RXRA; PSIP1; STAT1; PEG3; PFDN5; KMT2A; CEBPD; BCL11A; MYB; ATN1; ZBED2; NAB2; PBX1; CREB3L2; EYA2; MNDA; SOX9; TCFL5; KLF11; TRPS1; NR4A3; TCF4; SSBP2; JUP; KLF10; OSR2; ARID4B; TCF7L2; FOXO1; KAT2B; ZNF117; GATA2; WT1; ATF3; ZNF415; DACH1; TWIST1; TBX3; VPS72; MYBL1; ZFP36L2; TOB1; ARID5B; JUN; AEBP1; POU2AF1; SCAND1; ZBTB18; NFE2L2; DAXX; HOXA5