Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID72027	Febuxostat	GSE92742	PHH	Human	24h	10uM	EID0388

Response Information :

Types	Number	Response transcription factors
Up-regulation	137	PPARG; ETV1; EGR2; ORC2; MED1; NRBF2; PBRM1; PHOX2A; TLX2; E2F2; ZNF177; NFKBIA; NRIP1; ZMYM2; SATB2; TRAK1; BAZ1A; ZNF468; PPARGC1A; MITF; ZNF124; FOXO3; NCOA4; ZNF813; YBX1; FHL5; BCOR; AATF; TAF12; TRIP4; BRPF1; XBP1; BIRC2; GCM1; CCNA2; ZFP64; TBX2; CEBPA; ADNP; THAP1; CREB3; ZNF12; SALL1; TOX4; RNF14; SND1; REPIN1; DR1; AFF1; ESRRA; ZNF146; HOXD10; NEDD8; HOXB7; ISL1; MYCBP; PSMD9; ATF5; EGR3; ZNF189; UBE2I; TMF1; BTG1; MLXIPL; MECOM; FLNA; RBBP4; TRIM32; PCBD1; RBM14; UBE3A; TAF10; MBD2; FOXO4; ID2; ZNF410; SNIP1; BLZF1; KAT6B; ZNF443; HMGN3; ZEB2; CREB3L1; TBL1XR1; CAMTA1; BHLHE41; TLE1; GATA2; MED20; ASH2L; ZNF83; SATB1; MAF; RNF10; KLF6; BCL10; TBPL1; TP53; COPS2; ZNF426; ZBTB1; MAFB; CRK; IKBKAP; NR1D2; MTDH; HOXA5; NR1H2; SCAND1; TRIM22; ATF4; MNDA; NCOA3; STAT5A; ZBTB38; TFEC; CCNC; APEX1; SMAD3; BATF3; IRF8; PIR; CITED2; YWHAB; JAK2; SOX11; ENO1; ID1; ZFPM2; SP140L; HDAC1; TWIST1; BASP1; KLF5; TRIP6; PDLIM1; KDM5D
Down-regulation	188	MKL2; TGFB1I1; CTBP1; ESR1; FUBP1; TULP3; BANP; SETD2; SOX2; MED21; SMARCD2; NFIC; ZNF589; SPDEF; MXD1; ZSCAN18; NCOA1; LZTR1; MAK; CBFA2T3; HOXB3; ZNF467; TAL1; IRF6; HOXC13; TERF2; RAD21; BCL3; GRHL2; WHSC1; HES1; THAP11; CNOT3; ZNF74; IRF9; MAZ; SMARCD1; TEAD4; FOXJ1; ATN1; PHF1; ID4; BCL11A; HIPK1; OSR2; JUND; CEBPD; UBP1; VEZF1; MED25; HIRA; SHOX2; WDR77; AR; YEATS4; TAF6; CDK2; TAF1C; HOXB2; BRD3; NFE2L3; ING4; CTBP2; ELK4; ZHX2; TCF3; SMARCB1; VGLL1; SSBP2; ZNF768; TCEA2; HMGB2; BACH1; FOXF1; TCF25; LOXL2; ZNF587; NR2F1; EHF; PLAG1; CITED1; HOXA11; RBL2; SMAD1; LDB1; TCFL5; ZFHX3; HINFP; CRY1; YBX2; HIVEP1; HMGA1; PFDN5; CDX2; ATF3; HOXC4; ERG; CHD9; CERS4; BRD7; ARID5B; LHX6; HHEX; FOXA2; CCNE1; CBFA2T2; ZNF652; MNAT1; MEIS2; ZNF580; TFAP2C; THRA; MYBL1; SALL2; TCF7; YAP1; SMARCC2; ZNF91; ABL1; ZMYND8; DLX2; PAXBP1; LMCD1; HIVEP2; SUB1; AEBP1; SRCAP; NFIL3; PEG3; ERBB4; PHIP; NFE2; SSBP3; KLF10; HIPK3; MSX1; ZNF394; ZNF423; HOXB6; ZBED2; JUP; NAB2; DACH1; PBX1; ARL2BP; ZNF274; TGIF1; ARID1A; RNF138; ELK3; TFDP1; SMARCA1; JUN; FOXF2; SOX17; GATAD2A; ZIC1; PRDM2; TCERG1; PBXIP1; ZBTB16; ACTL6A; PAWR; TCF4; RXRA; PLAGL1; RORA; SOX9; ELF3; ZBTB18; YBX3; TBX3; FOXM1; FOXE1; TRPS1; TOB1; CD3D; LITAF; GATA6; NR2F2; MYB; CBX6; NFATC4; CREB3L2; POU2AF1; ZNF586; ZNF331; SPEN