Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID71980	Maprotiline	GSE92742	PHH	Human	24h	10uM	EID0388

Response Information :

Types	Number	Response transcription factors
Up-regulation	138	ZNF532; PAX8; ATF7IP; BCOR; FOSB; CREBZF; ZNF512B; FOXF1; IKZF3; PRMT2; SMAD1; CDK9; SOX12; ISL1; HIVEP1; CBFA2T3; TLE4; SOX13; BACH2; ZSCAN31; FLI1; TERF2; SOX18; LEF1; TSC22D2; PEX14; HR; STAT2; BACH1; JUND; ZNF529; NR4A1; ID3; WT1; TOX; MLXIP; TAL1; MDM4; MED1; NR4A2; ZBED2; CBX7; NR2F1; FHL2; SIX1; SMARCA4; MNT; TFAP2C; ETS2; ING2; TRIM22; KLF1; ZMYM2; CHD7; AFF1; SMARCA1; TOX3; KLF6; SOX11; FUBP1; FOXA1; NPAT; BAZ2A; ZSCAN18; TCF21; SMARCC2; HIC2; CAMTA1; TFAP2A; FOXN3; KLF10; KAT6B; BAZ1A; PSMD9; HOXB6; TGIF1; ZNF217; SMARCC1; ID2; TERF1; WWC1; CITED2; TBX3; ZNF107; APEX1; C1D; ZNF329; FOS; DDX17; TTF2; TXNIP; SAP30; MED24; SMAD3; KMT2A; PRKDC; HOXB5; MYCN; ARID4B; FOXM1; BASP1; ID1; CCNE1; MAGED1; TBL1XR1; BTG1; EGR2; GATA2; SSX1; MYBL1; ATF3; TCF4; JUP; MITF; SOX17; NR3C2; FOXE1; RBPMS; SLC2A4RG; MYCL; BIRC2; ARID1A; HMGB2; MEF2C; JAK2; ASCL1; ZFPM2; FOXJ3; TOB1; KLF4; PAX5; ZFP36L2; DACH1; ZNF331; ERBB2; NR2F2; ERBB4; KDM5D
Down-regulation	114	MYC; ZKSCAN1; CDC5L; ZNF160; ZNF611; MLXIPL; ZNF721; RBBP7; GATA4; MYRF; TCEA1; PREB; RBM39; RORC; CXXC1; ZNF337; RING1; GATA6; NR1I3; ZNF574; MYNN; SNAI2; HES1; ZNF665; RARG; CTNNB1; ZNF552; HDAC2; NKX3-1; AIP; PRRX1; ITGB3BP; NR1H2; RUNX1; GTF3A; CEBPD; SIRT2; MAFG; DEK; XRCC6; ZBTB16; FOXD1; SUPT3H; NR2C1; SMARCD3; ZNF688; ZNF32; MECOM; FOXA2; ZNF45; CNBP; ZNF430; SATB2; ZNF580; ZBTB38; TMF1; ZNF44; ZNF394; CRK; PBX3; CREB5; SSBP2; ZIC1; ARNTL2; TAF10; MLX; CREG1; PHF20; ZNF593; ATF6; NR2F6; PPP1R13L; ASH2L; LITAF; HOXA4; DMTF1; TBX2; TCFL5; PSIP1; TRIM16; ZMYND11; IRF7; ALX1; BMI1; HIVEP2; PNRC1; HBP1; KLF5; ZNF22; NFATC4; TRIM28; HLX; NR1D2; BATF3; RLF; TBL1X; PAX6; ARID5B; ETV5; NFE2L2; DAXX; ZNF131; HLTF; SPEN; MSX1; SP140L; MAFB; ZNF586; BRD2; AEBP1; PEG3; HTATIP2; HOXA5; PDLIM1