Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID71972	Tranilast	GSE92742	PHH	Human	24h	10uM	EID0388

Response Information :

Types	Number	Response transcription factors
Up-regulation	302	HOXC10; SUV39H1; RELB; FOXD1; DPF2; SATB2; EHF; UBP1; ADNP; ZHX3; PPRC1; EGR2; POU2F2; TERF2; AGO2; BATF; PLAGL2; TSG101; PAX9; SUPT6H; MSC; MED31; REPIN1; MED1; SMAD6; E2F2; E2F1; NFYC; KAT5; PPARG; GFI1; PHF8; BAZ1B; SERTAD2; SOX13; MYB; ZBED4; RUVBL2; BAZ2A; KMT2B; DLX6; DYRK1B; RUNX3; BRF2; PPARGC1A; SMARCA1; ZBTB18; HOXB7; ZBTB39; PARP1; ATF7; KLF12; LZTS1; RARA; THAP1; SKI; IKZF1; SNAPC4; MMS19; VGLL1; HDAC5; WHSC1L1; NEUROD1; NR1D2; TXNIP; SF1; RSF1; BCLAF1; MYC; SFMBT1; OLIG2; CBX2; TLE2; TAF4B; HDAC4; NPAS2; MLX; NR2C2; RELA; NACA; HMG20A; SFPQ; NRBF2; SCMH1; HDAC1; TRAF6; GMEB2; HNF4A; HIPK3; ZNF576; PSMD9; STAT5B; ZNF132; STAT6; ZNF557; PLAG1; NAB1; SREBF2; PRPF6; ZNF473; HOXA10; CENPB; JUND; TAF4; ADRB2; MNX1; ARID4A; NAB2; BLM; ZBTB24; FOXA1; SIAH2; SHOX; FOSB; VDR; PIAS3; SMAD5; DMRT1; ZNF16; BMI1; SP1; NKX3-1; SNW1; CHD3; EN2; EYA2; TCF3; UBE2L3; RUNX1; POLR2A; MTF1; HLF; ETV5; ZMYND11; TAF10; ESRRA; ETS2; SNIP1; HMGA1; PPP1R13L; MECP2; UBE2B; HR; ZIC1; BRD2; EGR1; ZNF587; BASP1; NR1H3; GTF2I; ESRRG; WWP1; GCM1; ZNF227; NR1I2; MITF; TRPS1; PKNOX1; ARID3A; TFCP2; PSMC3IP; ARNT; DDX17; RBL1; TAF1A; TFEB; ATF7IP; CEBPA; SIM1; CALR; NCOA4; EGR4; CBFA2T3; SSX1; PURA; TWIST1; MBD2; MEF2A; IRF2; RERE; PROX1; TFCP2L1; ZBED2; KLF4; GABPB1; BCL3; ZNF22; TBX1; AATF; ZNF124; ZNF146; POU4F1; ZNF528; SIX1; ACTL6A; FOXG1; FOXJ3; SMAD7; ZNF112; KAT7; SMARCA4; NFE2; RNF14; SOX4; BHLHE41; IRF1; NONO; YBX2; TRIM28; PREB; TFAM; HCFC1; TBPL1; HOXA1; SSRP1; RBM14; CDX2; KDM2A; SUPT4H1; SUMO1; XBP1; ING2; YBX1; TP53; CEBPZ; ZFP36L2; ELF4; ELF3; ASH2L; TSC22D3; NEDD8; ATN1; SMAD2; JUNB; SMARCA2; MAZ; SP140; ZNF443; MYT1; FHL2; FOXM1; HDAC9; TSC22D4; ERF; CCNA2; TFDP2; SPIB; HOXC4; TRIM22; NFKBIA; AFF1; EN1; TCF21; SND1; FOXO1; ASCL1; TOB1; HIPK2; TCERG1; TFEC; RUVBL1; CBX5; PBX2; TFAP2C; MED20; PCBD1; NCOR2; HMGXB4; E2F5; NKX2-2; ZNF580; MYCBP; TCFL5; SAP18; IRF4; KDM5A; STAT5A; SOX10; LPIN2; SOX9; BRD4; HLTF; E2F8; BATF3; SMARCA5; CDK2; TBL1XR1; LMCD1; SLC2A4RG; FOXE1; PIR; PITX1; NFATC4; RHOA; CRK; ENO1; PAX5; PLAGL1; NFE2L2; SP140L; ID3; MYBL2
Down-regulation	281	MTF2; NR2F6; ZNF573; ETS1; CDC5L; ZNF611; CARHSP1; ZNF160; ZNF133; ZNF721; FUBP1; ZNF562; SCAI; ZNF44; ZFP36L1; NRIP1; CERS4; ZNF43; ZNF32; EHMT2; THAP11; ZNF91; ZNF84; ZNF83; ISL1; RBFOX2; HIRA; TCF7; ZNF688; ZNF500; MXD3; NEUROD6; ATF3; RORA; POU2F1; ZNF3; POU5F1B; YBX3; ZNF337; ZMYND8; BANP; ZNF224; ZNF426; LIN28A; ZNF665; REL; CRY1; CAMTA1; ZNF669; TCEA1; IRF7; SMARCD3; HMGB2; HSF4; ZNF331; ZNF512B; EZH2; NR2C1; SUPT3H; ZNF85; MAFG; PHOX2B; RFXANK; ZBTB20; CBX3; ZNF354A; ZNF423; HMBOX1; ZNF652; FOXJ1; ZNF467; ACTL6B; CEBPD; WDR77; DEAF1; MAK; TDRD3; USP21; PHF1; ZNF140; FOXK2; LOXL2; TGIF1; CHD8; DACH1; CHD9; MED13; PRDM14; HESX1; TEAD3; DR1; MAFB; TAF11; NFRKB; CTCF; ZNF135; NFKB1; ZKSCAN3; FLNA; PRDM4; ZNF254; MEIS2; ENY2; ZNF136; PRDM12; DEK; ZNF654; ZNF174; RBBP8; PRDM10; GFI1B; TDP2; ZNF165; UBE3A; ZNF430; PIAS1; RNF138; THAP3; MEIS1; ZKSCAN1; MKL2; NR4A1; NR1H2; CNBP; ZNF358; SALL2; TULP3; NANOG; IRF3; FLI1; ZNF184; CNOT1; ITGB3BP; SIX3; ZNF529; ZNF12; PEX14; ZNF273; ZNF302; RBBP4; BRD3; CTBP1; ZZZ3; KDM4C; ARID5B; ZEB1; HBP1; RREB1; ZNF248; L3MBTL1; HIVEP1; CDYL; TCEB2; PSIP1; URI1; SOX17; ZSCAN18; HES1; AES; TTF1; RNF111; PTRF; SSBP2; ZMIZ1; ZNF219; ZNF232; CXXC1; BARX1; TLE1; TRIM29; TBX3; BIRC2; PMS1; DNMT3B; ZNF131; MNDA; MEOX1; E2F3; ZFPM2; DDIT3; STAT1; PKNOX2; IKBKAP; THAP4; ZNF268; YWHAB; ZNF589; YEATS4; ABL1; TCF4; MEF2C; KAT6B; KLF6; ZNF551; UIMC1; ZBED1; PBXIP1; RBPJ; ZNF117; SUB1; TAL1; LDB1; ATF2; HMGN3; TRIM24; NR4A2; MXD4; CUX1; THAP7; DAXX; PHF20; TGIF2; NR2F2; CREM; MEOX2; RBM39; CDK9; CCNC; MYCN; LEF1; LITAF; HEY2; PRKDC; ERG; PEG3; BTG1; PNRC1; MAF; ZNF667; MXI1; NR0B1; ARL2BP; EYA1; TLE4; INSM1; MBD4; KLF11; ERBB4; ESR1; EP300; IRF8; TBX2; CNOT2; ZNF264; AHR; MECOM; NR5A2; DLX2; ID4; ERBB2; DMTF1; PSMC3; SCAND1; FOXC1; AR; HHEX; GATA2; CBFA2T2; TULP4; KLF2; ARID4B; APEX1; TP63; HOXA5; IFI16; SOX11; ZNF415; CITED2; IRF6; EMX2; HMG20B; NCOA2; KAT2B; AEBP1; KLF5; WT1; ELK3; PBX1; HTATIP2; BHLHE40; POU2AF1