Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID71943	Mek1-2-inhibitor	GSE92742	PHH	Human	24h	10uM	EID0388

Response Information :

Types	Number	Response transcription factors
Up-regulation	96	ZBED2; ADNP; TBX2; ZNF211; RREB1; TCF21; MEN1; BRD7; MBD2; FHL2; INSM1; CBX7; ZSCAN31; AFF1; UBE2B; BAZ2A; FOSL2; SATB2; ARID4B; BNC2; HOXB7; NR1D2; URI1; PTRF; EYA2; ZNF274; ZNF304; ST18; RNF6; MYRF; WWC1; PAXBP1; CITED1; ZNF667; ZNF217; SP3; FOXK2; SHOX2; BHLHE41; FOXF1; RNF14; COPS2; FOXA1; CHD1; ZBTB1; SMARCA5; SSX1; DDX17; TFDP2; SREBF1; TLE4; SP140; NAB1; MAF; SP140L; CTR9; NKX2-2; TFDP1; NFE2L2; TOB1; TRIM16; ZBTB43; EGR2; INSR; ZBTB38; SMAD2; ZNF83; FOXF2; SAP30; ZNF264; TFEC; TCERG1; MXI1; SATB1; RNF10; KAT6B; PEG3; BBX; HMGB3; SOX11; BATF3; IKBKAP; NCOA3; CCNC; WT1; IRF1; ZNF131; MYB; CHD7; TRIM29; JUP; SMAD7; CITED2; PAX5; PITX1; POU2AF1
Down-regulation	75	CRYM; ZNF205; CHD8; POU5F1B; YEATS4; RBPJ; FOXJ1; NUP62; MAZ; PMF1; ZNF768; ARID5A; PPARGC1A; ZNF721; MLXIPL; STAT3; TAF6; ZNF160; HDGF; IRF7; JARID2; ZMIZ2; SOX10; ING4; NFIC; CTBP2; MED13; GATAD2A; JUND; PPARD; BCL6; CENPF; MSX1; HOXB6; SIX1; RORA; PCGF1; SPI1; ANKRD1; DMTF1; DNMT3B; SND1; NFIB; ABL1; NFIL3; EGR3; ELF5; ZNF384; EZH2; SSBP2; CUX1; GCFC2; KLF10; CD3D; TCF7L1; PBXIP1; NCOR2; ACTL6A; NR0B1; SLC2A4RG; SOX17; MYBL1; JUN; TCF4; GTF3A; ATN1; FOXC1; FOXM1; NKX2-1; ZIC1; MYBL2; ERBB4; SPEN; TXNIP; HOXA5