Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID71887	3-methyl-gaba	GSE92742	PHH	Human	24h	10uM	EID0388

Response Information :

Types	Number	Response transcription factors
Up-regulation	171	ZNF189; RUVBL2; MED6; REPIN1; HOXB7; DPF2; CEBPA; AFF1; NFKBIA; PARP1; TSC22D3; CREG1; ORC2; XBP1; APEX1; RBBP5; NEDD8; HCFC2; MAGED1; ZNF23; CREB5; TRIM16; PPARGC1A; PMF1; HNRNPD; MED4; SIX1; ELF1; NRIP1; PPRC1; PAX8; ZNF536; ZBTB38; PSPC1; TRIM28; TFEB; SCMH1; TBL1XR1; TRIM32; SKI; NR1D2; USP22; RELB; MED1; USF2; PCBD1; RBBP4; SMARCA2; GABPB1; FOXO4; RBM14; TSC22D1; FOXO3; BHLHE41; CASZ1; NCOA4; NKX3-1; MAF; GTF3A; TP53; ZNF184; PIAS2; ATF5; SALL1; HLF; NFIL3; MMS19; MTDH; PA2G4; ZNF410; MTA1; NFE2L1; ZNF160; NFAT5; SSBP2; KLF2; ZNF593; MED24; TLE1; FOXJ3; NLK; TRIP6; ID2; IKBKAP; MAX; CCNA2; SREBF1; PRKDC; YBX1; FLNA; TLE4; SNIP1; ZNF146; ZFP36L2; SF1; SATB1; KAT6B; HLTF; BCL3; TCF7; RNF10; BAZ1B; ATF4; EDF1; JARID2; MITF; SND1; WWTR1; YWHAB; SLC2A4RG; SMARCE1; MYCBP; NFYC; ID1; PATZ1; ENO1; KAT7; BMI1; RORA; POLR2A; SAP18; ZMYM2; ERG; DNAJC1; SATB2; NRBF2; ZNF12; PIR; RBPMS; SMAD6; EZH2; GATA2; STAT5A; EMX2; CERS6; NR3C2; HDAC1; FHL2; NCOR2; PCGF2; PSIP1; LPIN2; HMGB1; CRK; ERBB2; HOXA5; BBX; MSX1; NR4A1; ETV5; RHOA; ETS2; RLF; TFEC; CD3D; BASP1; IRF1; TWIST1; FOXO1; MEF2C; ABL1; SAP30; ZEB2; TRIM29; ID3; NFIB; AHR; KLF4; CALR; PDLIM1; KDM5D
Down-regulation	165	SPDEF; NHLH1; SUZ12; LHX3; MKL2; PRDM12; MAP3K10; ZNF215; WDR77; RCOR3; ESR1; ARID3B; NEUROD6; ZSCAN18; FEV; CAMTA2; GFI1; OVOL2; ERBB4; ZSCAN16; NFIC; HIPK1; FOXH1; PBX3; VGLL1; INSM1; SHOX2; MXD1; DLX2; RING1; ZNF552; CTBP2; MEIS2; ZNF562; ZNF266; FOXJ1; RORC; VDR; SSBP3; ID4; TOB1; ELK4; ZNF232; SHOX; HOXB1; FUBP1; PHIP; STAT3; KLF9; ASCL1; GATA6; NFIX; HOXB2; ZIC3; HOXD3; NFYB; IRF6; KLF13; ZBTB18; SOX2; ZNF85; TERF2; ZKSCAN1; MYCL; ZNF589; ZNF195; NFE2L3; GATA1; ZNF816; ZNF140; OLIG2; SUMO1; NFX1; STAT4; CHD9; ZNF467; PSMC3IP; TCF21; ZNF211; NPAS2; PCGF3; E2F4; CHD7; WT1; ZNF528; BCL11A; FOXI1; ZNF606; PFDN5; TAL1; BACH1; BRD3; MAML1; PLAG1; INSR; CDX1; NFATC3; KLF11; PEG3; IRF9; EHF; ZNF667; SRCAP; LIN28A; AEBP1; PROX1; CCNH; NEUROD1; PAX6; NFATC4; NCOA1; HHEX; TULP3; TFAP2A; TCERG1; RNF138; MEIS1; DACH1; CBFA2T2; PAXBP1; CDK2; HOXC4; NR2F1; NAB2; EN1; ZNF239; CRYM; IFI16; MYB; HOXD1; HIPK2; ZNF665; FOXF2; HMGB2; RBBP8; STAT1; PRRX1; TFDP1; ZMIZ1; EYA1; ZNF117; SOX11; MYBL1; ELF3; BRD4; TCF7L2; ZBED2; ZNF91; SALL2; HSBP1; ATN1; IRF4; HLX; SOX17; ZNF415; TCFL5; DMTF1; ZNF586; MYBL2; ZNF274; MXI1; ZNF331; ZFPM2; JUP; PBX1