Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID71886	Metolazone	GSE92742	PHH	Human	24h	10uM	EID0388

Response Information :

Types	Number	Response transcription factors
Up-regulation	78	TCFL5; KAT5; MYC; NKX3-1; NRIP1; SIX2; HCFC2; EED; ETV5; PIAS2; CD3D; AGO2; TOPORS; EGR4; ATF5; ELK1; CARHSP1; HMGA1; MAX; ZNF468; NKX2-2; DR1; GATA2; TBL1XR1; MED1; MED4; MDM4; POLR3F; NFKBIA; HTATIP2; CCDC59; SALL1; HAND1; ZNF12; ZFP36L1; NRBF2; NFYC; PIR; NPAS2; PCGF1; RNF141; BCL11B; KLF2; MTDH; MYCBP; KAT7; SATB1; USP22; STAT5A; ZNF410; CBX3; LPIN2; CREG1; HLF; SSX1; TRIM28; WT1; C1D; EZH2; RBBP4; TRIP6; PCBD1; SLC2A4RG; ZNF226; TBPL1; NCOA4; IKBKAP; CCNA2; SP140L; MITF; DRAP1; EGR2; HDAC1; EYA2; LEF1; BATF3; EMX2; KDM5D
Down-regulation	124	GTF2A2; ZKSCAN1; SUZ12; BRCA1; ARID3B; NCOA1; ZMYND8; LOXL2; KLF9; NHLH1; CHD9; VEZF1; PBX3; FUBP1; ZNF91; ZNF665; HES1; ZBTB40; ZNF160; PHIP; ZNF611; IRF9; ZNF248; GTF2F1; PBX1; ZNF573; E2F8; DDX5; RNF111; ZNF589; ZNF430; SOX9; ID4; ZSCAN9; NFE2L3; BNC2; HOXB6; EZH1; ASCL1; BCLAF1; CENPF; RERE; CDYL; ZNF93; ZSCAN18; CTBP2; ZNF721; INSM1; RBM39; DACH1; PMS1; SHOX2; IRF7; FOXL2; PAXBP1; CREB3L2; ID1; ZNF224; IRF6; ZBED2; ZEB1; CRK; ZNF587; AFF1; ZNF195; IRF4; ZNF266; MED17; TP63; NR2F1; LMCD1; ZNF394; ZMIZ1; ESR1; DEAF1; KDM5C; PCGF2; TFCP2; TCF4; ZNF43; PLAG1; BRD7; ATF3; NR2F2; ERBB4; CHD7; ZNF24; DDX17; SSBP2; KAT6B; NCOA6; KLF6; SMARCC2; TOX3; NFATC4; PAX6; ZNF117; ZBTB18; BCL11A; KLF10; FOXE1; SOX11; DMTF1; BRD4; SOX4; TRIM22; DLX2; MYBL1; RBBP8; RHOA; TXNIP; JUN; ZNF652; PEG3; TBX3; LITAF; KAT2B; MYB; TRPS1; MXI1; ZNF586; DAXX; MYBL2; POU2AF1