Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID71879	Meclizine	GSE92742	PHH	Human	24h	10uM	EID0388

Response Information :

Types	Number	Response transcription factors
Up-regulation	113	ECD; RELB; REPIN1; CREG1; LZTS1; MED6; NFKB1; NKX3-2; INSM1; TBP; USP22; FOXF1; MEOX2; NKX2-2; EGR2; EGR4; ZNF189; PIAS2; RBM14; ZNF410; RELA; CASZ1; GTF2IRD1; SMAD2; ERG; IL16; HOXB7; HNRNPD; HOXB13; NR1I2; MED12; CBFB; CEBPA; MED23; SIX1; SNW1; ASH2L; BHLHE41; NONO; SFPQ; PHF8; TBX2; GFI1; CAMTA1; UBE2I; TFEB; TGFB1I1; SMARCC1; FOXO4; XBP1; TSC22D2; PCBD1; ISL1; MTDH; EGR3; FOXO3; INSR; HAND1; UBE2B; UBE3A; FHL2; MBD2; GABPB1; NPAS2; NFE2L1; BBX; RBBP4; IKBKAP; TOX3; PIR; CCNA2; NR3C2; HDAC1; RYBP; NFYC; RNF10; NRBF2; ZNF267; MED24; ERBB2; ETS2; NR4A1; KAT7; RAN; MYCBP; ID2; CCNC; CERS6; HOXD1; ZBED2; NR0B1; C1D; FOXO1; ERF; SP3; COPS2; ZNF165; ARID4B; MAF; SMAD7; PRKDC; HLF; KLF2; TFAP2A; RUNX3; BMI1; TGFB1; IRF8; SLC2A4RG; BASP1; ETV5; TRIM29; TFEC
Down-regulation	153	ATF5; SPDEF; MTF2; PGR; RCOR3; STAT4; OSR2; STAT3; CAMTA2; ESR1; WDR77; ZNF195; NFIX; NCOA1; FOXL2; AR; MKL2; NFE2; EHMT2; NKRF; HOXA11; FUBP1; SOX2; TAF1A; GTF2I; CHD8; ZFP36L1; CBFA2T3; ZNF85; POLR3C; CLOCK; ZNF266; HABP4; ZNF688; MEIS2; ZNF93; PSMC3IP; CTBP2; ZNF593; ID4; ZKSCAN1; IRF3; IRF7; ZNF202; ZBTB16; PMS1; NFIC; KDM4C; CUX1; MYBL1; ID1; ZNF43; MED17; ZNF816; ARID5B; YAP1; FOXJ1; PLAG1; PHIP; RBBP8; PSPC1; SSBP2; RBL1; ZNF239; OVOL2; HMGA1; DLX5; SSBP3; DLX2; GCFC2; CNOT3; PAWR; ZBTB18; TRIM33; ATF3; EN1; PFDN5; HIVEP1; KMT2A; TCF3; TCEA1; TTF2; PSIP1; TFAP2C; CDK8; ZIC1; HDAC9; KLF9; EMX2; IRF9; ZNF232; LIN28A; ZMIZ1; ERBB4; HIPK2; PAX6; RUNX1; ELK3; CUX2; ZNF665; ARID1A; NR2C1; HOXB2; ZNF22; TAF1D; KAT2B; JUND; NFATC4; SALL2; ZFX; GATA2; SOX17; ZNF415; ZNF430; PBX3; IRF4; ZFP36L2; NCOA2; ZFPM2; TOB1; TP63; TULP3; BRD4; ZEB1; MYB; NR5A2; HMGB3; TFDP1; VPS72; SALL1; NFIB; MYBL2; HBP1; NR4A2; RXRA; ZNF331; ZSCAN18; TBX3; TCF7L1; STAT1; TRPS1; KAT6B; PBXIP1; WT1; SPEN; NFE2L2; DMTF1; MSX1; BCL11A; VGLL4; MEIS1; DACH1; HOXA5