Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID71829	Brinzolamide	GSE92742	PHH	Human	24h	10uM	EID0387

Response Information :

Types	Number	Response transcription factors
Up-regulation	150	EPAS1; AGO2; WNT4; ZHX2; ELK4; TOB1; CREB1; TRIM29; SOX9; CBX4; TLE2; KLF9; CREB3L2; NR2F1; ID1; ZNF180; ZNF652; FOXF1; BPTF; IL16; GATA1; GTF2I; NR4A2; EHF; ZKSCAN8; IRF8; TAF1; ZNF165; DAXX; ZFP36L2; YAP1; IRF4; ZBTB20; MAML1; PLAG1; ZNF623; CSDE1; SMARCA1; LEF1; ZNF354A; GTF2IRD1; CDX1; MED13; RBFOX2; MBD1; ERF; RBL2; LHX3; ZNF532; TCF21; DBP; CBX7; IRF1; ZNF556; RARG; IRF2; CHD7; HBP1; CREBL2; CDK8; MECP2; SOX15; CHD9; MED14; PTRF; ZFP36L1; TERF1; BAZ2B; JUP; CAMTA1; TGIF2; NPAT; SMAD4; EZH1; INSM1; FOXO1; JAK2; MKL2; FLI1; IFI16; TBX2; L3MBTL1; CEBPD; JUNB; HOXD3; CBFA2T2; PITX1; LOXL2; RARB; ID3; IRF9; MZF1; FOXA2; IRF6; THAP11; HOXD1; LITAF; SHOX2; ZBED2; RAD21; ERBB2; ZNF112; TRPS1; MEOX2; ST18; SMAD3; ZBTB38; HMGB2; BCL11A; TCF7; NFATC1; SOX17; ZFHX4; ZNF224; ZFPM2; ZEB1; HMBOX1; TRIM16; ZNF589; ARID4B; NR1D2; ISL1; TFAP2A; ASCL1; SOX11; CREM; NCOA3; TFAP2C; BACH2; TP63; TRIM22; ZNF91; MEF2C; PBX1; PIR; ZNF423; BNC2; BCL11B; MNDA; HMG20B; ID4; ZNF331; TAL1; NFE2L3; TSC22D2; MEIS2; CCNE1; ESR1; ZMIZ1; BASP1
Down-regulation	145	HDAC2; HSBP1; CCNC; PA2G4; ZNF580; TFDP2; MED27; NEDD8; GTF2F1; MLX; INSR; TTF1; ATF4; ZNF646; XRCC6; ENO1; RHOA; RBPJ; TAF10; ETV5; ZBED1; TSC22D1; CITED2; TFEC; CRYM; ZNF273; YBX3; MAZ; RUVBL2; NELFB; TBPL1; PSMD9; ZNF133; CEBPA; OLIG2; MAGED1; UBE2I; ZEB2; TCERG1; NFIB; ZNF32; NR1H4; RB1; NKRF; CRK; ZBTB16; EDF1; TSC22D3; MYCN; EMX2; HOXA7; ZNF468; CNBP; HEY2; FHL2; TSG101; ZNF22; DDIT3; MAFG; PDLIM1; PFDN5; HOXB7; TOX; KAT6B; GATA4; TGFB1; ZMIZ2; AIP; GABPB1; TAF12; RNF10; IKBKAP; RBBP8; TRIM28; EGR2; CHD8; ZNF529; BTF3; BIRC2; NR1H2; CHD4; YWHAB; TCF12; ELK1; FOSL2; MYCBP; SETDB1; SSBP2; SMARCE1; NRBF2; RBBP4; TFAM; FLNA; SPEN; ILF2; RBBP7; HEY1; NFIL3; RBPMS; RYBP; SFPQ; CENPB; GATAD2A; STAT3; TBL1XR1; DRAP1; YBX1; DNMT3B; RORA; HDGF; HTATIP2; MLXIP; ID2; MED6; BTG1; RAN; FOXG1; NCOR2; E2F3; HOXB6; GATA2; NKX2-1; ZNF410; HMGN3; AEBP1; GTF3A; HLF; KLF2; VPS72; LMCD1; SATB1; NR0B1; BMI1; USF2; SAP30; EGR3; HMGB1; NFKBIA; NCOA4; MSX1; HLTF; SCAND1; ATF3; MYB; HOXB2