Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID71797	Febuxostat	GSE92742	PHH	Human	24h	10uM	EID0387

Response Information :

Types	Number	Response transcription factors
Up-regulation	150	CTR9; CBX7; SOX4; ZNF227; ETV5; ADRB2; STAT6; CREB5; NFYC; ATN1; TERF1; TRIM16; SNW1; EYA1; REPIN1; ERF; PTRF; MEOX1; ERCC2; NFIL3; TGFB1; ZFHX3; SP100; CIZ1; POU4F1; EHMT2; NCOR1; REL; XRCC6; ZFY; ASCL1; ZNF23; ORC2; ARNT; HDAC1; MAGED1; IRF1; TMF1; ELF3; APEX1; CDC5L; CSDE1; KDM5D; HMG20A; LITAF; SALL1; CENPB; NRBF2; ZNF45; GTF2IRD1; NR2C1; ECD; BCL3; ZNF184; ZNF268; MED6; TGIF1; TCF7L1; AFF1; YBX1; RCOR1; MSX1; DPF2; HDAC7; TRIM32; HMGA1; CALR; RFX7; TCF25; ZNF165; BMI1; ZNF146; TP63; TGFB1I1; ETS2; FOSB; FOS; JAK2; TSC22D1; CITED2; JUNB; TAF6; WWP1; HOXA5; NKX2-2; STAT5A; PSPC1; LOXL2; GTF3A; RNF111; COPS5; ZNF32; MAZ; HTATIP2; HMG20B; NCOA3; ARNTL2; TRIP6; MED23; PITX1; XBP1; ZBTB11; FOXD1; RNF10; NR4A3; SIX2; ZNF112; NR2F2; PLAGL1; PHF8; MGA; INSR; PIR; ZSCAN31; SMAD3; KLF2; KLF4; ARID1A; RUVBL2; MAFF; FOSL2; ELF5; YAP1; SOX10; FOXO4; CREB3L1; ZNF410; NR0B1; ATF4; SETDB1; FOSL1; NFAT5; PCGF2; SMARCA2; SATB1; BASP1; BRD4; ISL1; VPS72; EHF; KAT6B; HSF2; RBBP7; DRAP1; TBL1XR1; HMGB1; CHD9; IFI16; NRIP1; SOX11
Down-regulation	124	SUZ12; LEF1; SPDEF; GMEB2; NEUROG1; GATA1; PROP1; PAX6; VGLL1; ZNF189; RBBP8; SUMO1; ELK4; CD3D; HDAC11; PLAGL2; CSDC2; TFDP2; PRRX1; VEZF1; FOXG1; UIMC1; CHAF1B; POU5F1B; TWIST1; KLF1; TAF5L; BACH1; CBFA2T2; MED25; KLF11; ZNF215; AFF4; MKL2; SPIB; ETS1; LHX6; NEUROD6; HMGB2; ZNF444; KLF13; ENY2; E2F3; CDX1; REST; FOXK2; OVOL2; AEBP1; NAB1; TFDP1; BRD7; CTBP1; RNF6; WT1; RAD21; ZBTB18; FUBP1; HIC2; ZFP36L1; SHOX2; HOXD1; TAL1; TRPS1; ID3; RBM39; IRF6; ADNP2; PFDN5; ZNF239; MED13; ZNF701; KLF6; YEATS4; ILF2; TBX3; IRF7; ID1; ZNF432; CUX1; KLF9; DACH1; PBX1; BLM; ZEB1; ERBB4; TCF4; ZNF611; ZNF117; ZNF652; IRF8; SSBP2; ID4; SOHLH2; MYCL; HHEX; THRA; ZFPM2; HEY1; NKX2-1; ZNF589; ZNF721; HOXB6; ZNF160; DAXX; RXRA; SPEN; POU2AF1; SCAND1; ZBED2; HOXB2; SMAD1; CCNE1; MAF; ZNF264; MYB; ZNF586; CHD7; ZMIZ1; AHR; KLF10; ZNF544; ZSCAN18; ZIC1; MAFB