Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID71693	Isorotenone	GSE92742	PHH	Human	24h	10uM	EID0387

Response Information :

Types	Number	Response transcription factors
Up-regulation	130	TFCP2L1; ASCL1; NFKBIB; INSM1; REL; SPI1; STAT5B; OLIG2; PHIP; RAD21; SMARCA5; TAF10; LYL1; BTG1; SATB2; TCF7L1; VGLL1; CDYL; CNOT6; MDM2; PTTG1; NFE2; IRX5; BAZ1A; GABPB1; RFX5; ELK4; ZNF580; MTF1; JUND; RUNX3; TERF2; AFF4; TAF5L; TOX3; ZNF219; TAF1; EGR4; CDX1; ATF7IP; ZNF93; NR4A3; ZMIZ2; TMF1; NANOG; TGFB1; TRIM25; FHL2; MYCL; NFYC; KDM5C; NKX2-1; SMAD7; HEY1; MED14; FOXI1; RLF; MBD2; NKX2-2; CITED2; ELF5; FOXJ3; ETS1; SMARCB1; EZH2; MXD1; MSX1; CAMTA1; LIN28A; MNDA; NFAT5; RYBP; FOXO4; ARID3B; KLF4; HIPK1; NR4A2; TBPL1; HMGB2; RRN3; TCEB2; PFDN5; STAT4; ETV5; PSMC3; BATF; TRIM22; CD3D; RNF138; ST18; ESR1; ZNF331; NCOA3; FOSB; DACH1; BCL11A; BATF3; NFYA; ZNF43; MYT1L; CREM; ERBB4; ISL1; IRF8; ZEB2; HOXD1; GATAD2A; IFI16; PEG3; DLX2; FOS; ERG; ZNF432; MAX; SOX11; ID4; FLNA; TSC22D2; EHF; MYB; KLF10; ZNF423; KAT6B; SOX17; POU2AF1; PSIP1; MYBL1; MEIS2; MAFB; BASP1
Down-regulation	138	IKBKAP; TLE1; PARP1; HDAC1; HDAC4; ZNF189; C1QBP; PRKDC; USP22; NR2F6; RNF14; CBX7; WWC1; SREBF1; CRK; RREB1; ESRRA; URI1; LEF1; PCBD1; SRF; THAP4; CCNC; MYC; TRRAP; HOXA7; PAX6; ZNF84; VEZF1; NFE2L1; CBX3; TDP2; MYRF; BRD8; NR1H4; FOXN3; DDX5; PPARGC1A; CTBP1; ZNF148; ZNF512B; ZNF32; GTF3A; RNF6; WWTR1; ATF4; NR2C1; ENO1; MNAT1; RXRA; MITF; HLF; TFDP2; MNT; TAF7; TRIM29; GATA4; SLC2A4RG; ZBTB16; NPAT; HMGN3; ZNF3; FOSL2; ZMYND8; TSC22D1; TRIM16; CARM1; ATF5; TLE4; PATZ1; EWSR1; KDM4C; ZNF443; THAP11; REPIN1; EZH1; PRDM2; MEIS1; SOX9; NPAS2; E2F3; RNF10; BNC2; KLF13; NEDD8; ADNP; SIAH2; MED4; SPEN; PSPC1; ID1; FOXO1; SMARCA2; CUX1; TWIST1; SP2; MEF2C; RBBP4; BCL6; AFF1; ZNF302; BIRC2; RERE; SMAD6; HDGF; CREB3L2; NKX3-1; MLXIP; ZNF217; BMI1; SFPQ; HOXA5; HOXB7; CREG1; MECOM; CTBP2; NFATC1; RORA; GTF2A2; HOXB6; FOXC1; BACH2; TBL1XR1; ZMIZ1; ASH2L; RNF4; HIC2; ZBTB18; DMTF1; HMGB1; CBX6; GATA6; NCOR2; DNAJC1; ZSCAN18; ZIC1; PBX3; ZBED2