Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID71685	Pirinixic-acid	GSE92742	PHH	Human	24h	10uM	EID0387

Response Information :

Types	Number	Response transcription factors
Up-regulation	179	LHX3; HOXD1; HOXB1; PRDM12; IRF4; SOX2; INSR; PROP1; PTRF; PHIP; SHOX2; MED13; RUNX3; BPTF; ALX1; RORC; ZNF281; WT1; SRF; TCF21; GATA1; ELF4; FOXJ1; FOXA2; TFDP1; TOB1; ZNF394; ARID3B; SERTAD2; GBX1; EYA1; TRIM33; ELK4; NR0B2; ZNF239; SPDEF; ZNF652; IRF1; LITAF; ZNF337; CREB3L2; ZNF84; GLI3; NCOA2; ZNF556; CRTC1; ZNF671; ZNF512B; ZNF324; BATF3; KLF15; TCEA2; MTF1; TFAP2C; ZNF589; ZBED2; ZMYND8; BCL11A; CDIP1; CD3D; TAF5L; CDX1; ETS1; ZNF131; ZNF672; ZNF667; SMAD2; STAT4; CERS4; ATF3; TBX2; HOXD3; KLF1; IL16; SUB1; TRIM29; NAB2; PLAG1; HOXA11; RFX5; BARX1; EP300; KLF6; ZNF688; NFX1; ZNF215; WNT4; RNF138; ZNF274; ZNF331; ZNF467; CHD9; AEBP1; TCF7; PKNOX2; TGIF2; FOXE1; MED14; SNAI1; HOXB2; ELF3; HOXB13; NR4A2; CHD3; PIAS4; ZNF211; KLF13; TEAD1; LMCD1; ZNF195; ESR1; DLX2; TAL1; CBFA2T2; ZNF264; NKX3-1; ZNF606; KLF7; MYCL; NFE2L2; TAF10; ZBTB43; HMGB2; ID4; CITED1; ZNF426; JUP; FOXD1; IRF6; WDR77; BRD4; FOXK2; RLF; BNC2; PBX3; ZNF611; RRN3; IRF9; ARID4B; PHF20; PEG3; ZNF232; FOSB; ZEB1; ERBB4; SCAND1; AR; SOX17; MNDA; ZNF587; IFI16; ARID5B; PIR; ZNF419; NR4A1; NR1H2; TOX3; THAP11; CBFA2T3; NFATC1; TBL1X; JUN; ISL1; ZNF91; FOXC1; SALL2; ZNF217; FOXO1; KLF9; CCNE1; TRPS1; NFATC3; MEIS2; NR2F2; ZNF721; GATA6; ZNF160; KDM5D; ZNF586
Down-regulation	163	EZH2; CCNA2; HSBP1; MTF2; MED21; USP22; CCNC; DR1; RNF14; NR1H4; ZNF212; ITGB3BP; NEDD8; LOXL2; EMX2; MYCBP; FOXM1; VGLL4; SPI1; TSC22D1; MITF; XBP1; CAPN15; SAP30; RBBP4; RUVBL2; FOXG1; ZNF146; TBL1XR1; CNBP; ENY2; ZNF22; REPIN1; BRD8; MYC; TSC22D3; MED4; AES; MED15; RBM14; HDAC1; HOXA7; PCBD1; SMARCB1; TGIF1; ZNF226; BIRC2; FOSL2; MED7; FOXJ3; TAF12; TGFB1; NR3C2; TRAK1; C1D; ZNF12; E2F3; NR1H3; DEK; ZNF468; SMAD7; PA2G4; HIPK3; PRKDC; HOXB7; ILF2; ZEB2; E2F5; RHOA; PQBP1; RBBP8; VEZF1; FHL2; TFEC; HMGA1; GABPB1; TLE1; ORC2; NEUROD1; NONO; HMGB1; ZNF23; ZNF443; ID2; NFE2L1; PPARGC1A; PARP1; MBD4; HLTF; PIAS2; TRIP6; PMF1; NFIB; ACTL6A; DRAP1; MAX; ELK3; ABL1; CALR; NRBF2; HDGF; UBE2I; BCL6; SFPQ; ZNF148; TXNIP; SLC2A4RG; NPM1; SOX9; GTF3A; PEX2; ZIC1; SMAD4; MEF2C; SMARCE1; USF2; TBPL1; TRIM28; SSBP2; ENO1; MED6; NR1D2; SATB1; CARHSP1; LPIN2; ZBTB38; TRIM16; CEBPA; SMAD3; MYBL1; RORA; CREG1; TCF4; PAX6; RNF10; TCERG1; DNAJC2; ETV5; DAXX; HOXA5; TADA3; INSM1; ARNTL2; NR0B1; BHLHE41; MYBL2; PLAGL1; TLE4; MYT1L; KLF2; CREM; FOS; VPS72; DMTF1; IKBKAP; EGR3; ZNF423; AHR; MAF; BBX; NRIP1; ZMIZ1; MAFB